Impacts of exposure to humidex on cardiovascular mortality: a multi-city study in Southwest China

BMC Public Health

Research

Xufang Gao¹  Rong Xue²  Mingjiang Li³  Hongbin Zhu⁴  Shijuan Ruan⁴  Chunli Shi⁴  Yang Li⁴  Jianyu Chen⁴  Yue Wen⁴  Li Zhang⁴  Xianyan Jiang⁴  Yizhang Xia⁵  Wei Huang⁶ 

[1] Chengdu Center for Disease Control and Prevention, No.6, Longxiang Road, Wuhou District, 610041, Chengdu, China;Guangyuan Center for Disease Control and Prevention, No.996, Binhebei Road,Lizhou District, 628017, Guangyuan, China;Panzhi hua Center for Disease Control and Prevention, No.996, Jichang Road, Dong District, 617067, Panzhi hua, China;Sichuan Provincial Center for Disease Control and Prevention, No.6, Zhongxue Road, Wuhou District, 610041, Chengdu, China;Sichuan Provincial Center for Disease Control and Prevention, No.6, Zhongxue Road, Wuhou District, 610041, Chengdu, China;School of Public Health, Chengdu Medical College, No.783, Xindu Road, Xindu District, 610500, Chengdu, China;Zigong Center for Disease Control and Prevention, No.826, Huichuan Road, Ziliujing District, 643000, Zigong, China;

关键词: Comprehensive Index;    Humidex;    Cardiovascular disease;    Temperature;    Humidity;   

DOI  :  10.1186/s12889-023-16818-x

 received in 2023-05-09, accepted in 2023-09-22,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundMany studies have reported the association between ambient temperature and mortality from cardiovascular disease (CVD). However, the health effects of humidity are still unclear, much less the combined effects of temperature and humidity. In this study, we used humidex to quantify the effect of temperature and humidity combined on CVD mortality.MethodsDaily meteorological, air pollution, and CVD mortality data were collected in four cities in southwest China. We used a distributed lag non-linear model (DLNM) in the first stage to assess the exposure–response association between humidex and city-specific CVD mortality. A multivariate meta-analysis was conducted in the second stage to pool these effects at the overall level. To evaluate the mortality burden of high and low humidex, we determined the attributable fraction (AF). According to the abovementioned processes, stratified analyses were conducted based on various demographic factors.ResultsHumidex and the CVD exposure–response curve showed an inverted “J” shape, the minimum mortality humidex (MMH) was 31.7 (77th percentile), and the cumulative relative risk (CRR) was 2.27 (95% confidence interval [CI], 1.76–2.91). At extremely high and low humidex, CRRs were 1.19 (95% CI, 0.98–1.44) and 2.52 (95% CI, 1.88–3.38), respectively. The burden of CVD mortality attributed to non-optimal humidex was 21.59% (95% empirical CI [eCI], 18.12–24.59%), most of which was due to low humidex, with an AF of 20.16% (95% eCI, 16.72–23.23%).ConclusionsLow humidex could significantly increase the risk of CVD mortality, and vulnerability to humidex differed across populations with different demographic characteristics. The elderly (> 64 years old), unmarried people, and those with a limited level of education (1–9 years) were especially susceptible to low humidex. Therefore, humidex is appropriate as a predictor in a CVD early-warning system.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

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