Successful management of rare gingival metastasis from gastric adenocarcinoma: a case report and literature review

World Journal of Surgical Oncology

Case Report

Zhili Wu¹  Yan Li¹  Husheng Lu¹  Donglai Lv¹  Jun Tang²  Jun Xu³ 

[1] Department of Clinical Oncology, The 105 Hospital of People’s Liberation Army, 105 Hospital of PLA, 230031, Hefei, Anhui,, China;Department of Gastroenterology and Hepatology, The 105 Hospital of People’s Liberation Army, Hefei, Anhui, China;Department of Pathology, The 105 Hospital of People’s Liberation Army, Hefei, Anhui, China;

关键词: Gastric carcinoma;    Gingiva;    Neoplasm metastasis;   

DOI  :  10.1186/s12957-017-1215-3

 received in 2017-05-09, accepted in 2017-07-22,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundGastric cancer rarely metastasizes to the oral cavity, especially to gingiva. Only 18 cases have been reported worldwide to date. This paper herein presents the nineteenth case of gingival metastasis from gastric cancer.Case presentationA 75-year-old man who underwent a radical gastrectomy for gastric adenocarcinoma was admitted to clinical oncology center for gingival mass which was originally diagnosed as epulis. The subsequent positron emission tomography-computed tomography (PET-CT) and histopathological examination revealed a gingival metastatic adenocarcinoma originated from gastric carcinoma. Then three-dimensional conformal radiotherapy (3D–CRT) with synchronization and sequential chemotherapy demonstrated clinical benefit in this patient. Furthermore, this research reviewed the records of 18 cases of gingival metastasis from gastric carcinoma in English, Japanese, and Chinese literature, and summarized the clinicopathologic features of the disease based on previously published papers.ConclusionThis case suggests that gingival metastasis from gastric cancer is worthy of vigilance. Biopsy and immunohistochemical (IHC) staining should be used for the final diagnosis. Moreover, the patient with uncommon gingival metastatic lesion can be successfully treated by radiotherapy with adjuvant chemotherapy.

【 授权许可】

CC BY   
© The Author(s). 2017