Analysis of 116 cases of rectal cancer treated by transanal local excision

World Journal of Surgical Oncology

Research

Yuanxin Tang¹  Gaofeng Liang¹  Gongping Sun¹  Xiaoxia Li¹  Jin Meng¹ 

[1] Department of Gastrointestinal Surgery, The Fourth Affiliated Hospital of the China Medical University, No. 4 Chongshan Road, 110032, Shenyang, China;

关键词: rectal cancer;    transanal local excision;    survival;    recurrence;    radiotherapy;   

DOI  :  10.1186/1477-7819-12-202

 received in 2014-03-25, accepted in 2014-06-12,  发布年份 2014

来源: Springer

【 摘 要 】

BackgroundThe purpose of this research was to evaluate the therapeutic effects and prognostic factors of transanal local excision (TAE) for rectal cancer.MethodsWe retrospectively analyzed 116 cases that underwent TAE for rectal cancer from 1995 to 2008. A Cox regression analysis was used to analyze prognostic factors.ResultsThe survival times for the patients were from 14 to 160.5 months (median time, 58.5 months). The 5-year and 10-year overall survival rates were 72% and 53%, respectively. In all 16 cases experienced local recurrence (13.8%). Pathological type, recurrence or metastasis, and depth of infiltration (T stage) were the prognostic factors according to the univariate analysis, and the latter two were independent factors affecting patient prognosis. For patients with T1 stage who underwent adjuvant radiotherapy, there was no local recurrence; for those in T2 stage, the local recurrence rate was 14.6%. In addition, there was no difference between the patients who received radiotherapy and those who did not (T1: P = 0.260, T2: P = 0.262 for survival rate and T1: P = 0.480, T2: P = 0.560 for recurrence).ConclusionsThe result of TAE for rectal cancer is satisfactory for T1 stage tumors, but it is not suitable for T2 stage tumors.

【 授权许可】

Unknown   
© Sun et al.; licensee BioMed Central Ltd. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.