BMC Cardiovascular Disorders | |
The relation between neutrophil-to-lymphocyte ratio and coronary chronic total occlusions | |
Research Article | |
Ahmet Avci1  Bulent Behlul Altunkeser1  Ahmet Yilmaz1  Kenan Demir1  Fikret Keles1  Ahmet Ersecgin1  | |
[1] Faculty of Medicine Cardiology Department, Selcuk University, Konya, 42075, Turkey; | |
关键词: Chronic total occlusions; Neutrophil-to-lymphocyte ratio; SYNTAX score; | |
DOI : 10.1186/1471-2261-14-130 | |
received in 2014-07-10, accepted in 2014-09-23, 发布年份 2014 | |
来源: Springer | |
【 摘 要 】
BackgroundNeutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammation that correlates with cardiac events. This study assessed the association between NLR and the presence of chronic coronary total occlusion (CTO).MethodsThe study population included 225 patients, a control group (n = 75), a coronary artery disease group (n = 75), and a CTO group (n = 75). NLR was compared in the three groups.ResultsNLR levels were significantly higher in the CTO than in the other two groups (p < 0.001). Bivariate correlation analysis showed a positive correlation between NLR and SYNTAX Score, and multivariate logistic regression analysis found that NLR was an independent predictor of CTO. ROC analysis showed that an NLR cut-off of 2.09 could distinguish between patients with and without CTO (AUC = 0.74; 95% CI, 0.68–0.81), with a specificity of 69.3% and a sensitivity of 61%.ConclusionNLR may be useful as a marker of CTO.
【 授权许可】
CC BY
© Demir et al.; licensee BioMed Central Ltd. 2014
【 预 览 】
Files | Size | Format | View |
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RO202311105020162ZK.pdf | 535KB | download |
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