Health-related quality of life in patients with sickle cell disease in Saudi Arabia

Health and Quality of Life Outcomes

Research

Donna K. McClish¹  Wala E. El-toum²  Abdul-Rahman Jazieh²  Yosra Z. Ali²  May Anne Mendoza³  Hafiz Malhan⁴  Ahmad M. Al-Suliman⁵  Abdulrahman O. Gorashi⁵  Mohamed E. El-toum⁶  Majid Al Salamah⁷  Anwar E. Ahmed⁸  Ahmed S. Alaskar⁹ 

[1] Department of Biostatistics, Virginia Commonwealth University, Richmond, VA, USA;King Abdulaziz Medical City, Riyadh, Saudi Arabia;King Abdullah International Medical Research Center, Riyadh, Saudi Arabia;King Fahad Central Hospital, Jazan, Saudi Arabia;King Fahad Hospital, Hofuf, Saudi Arabia;King Saud bin Abdulaziz University for Health Sciences, P.O. Box 22490, MC 2350, 11426, Riyadh, KSA;King Saud bin Abdulaziz University for Health Sciences, P.O. Box 22490, MC 2350, 11426, Riyadh, KSA;King Abdulaziz Medical City, Riyadh, Saudi Arabia;King Saud bin Abdulaziz University for Health Sciences, P.O. Box 22490, MC 2350, 11426, Riyadh, KSA;King Abdullah International Medical Research Center, Riyadh, Saudi Arabia;King Saud bin Abdulaziz University for Health Sciences, P.O. Box 22490, MC 2350, 11426, Riyadh, KSA;King Abdullah International Medical Research Center, Riyadh, Saudi Arabia;King Abdulaziz Medical City, Riyadh, Saudi Arabia;

关键词: Sickle cell disease;    Quality of life;    SF-36;    Pain;    Saudi Arabia;   

DOI  :  10.1186/s12955-015-0380-8

 received in 2015-06-08, accepted in 2015-11-11,  发布年份 2015

来源: Springer

【 摘 要 】

BackgroundThere is a lack of research concerning health-related quality of life (HRQoL) in Saudi patients with sickle cell disease (SCD), particularly among adult populations. The aim of the current study was to describe the characteristics of SCD patients and their impact on their quality of life (QoL).MethodsSix hundred twenty-nine adult SCD patients who attended King Fahad Hospital in Hofuf and King Fahad Central Hospital in Jazan were included in the analysis. Demographic/clinical data were collected and an Arabic version of the Medical Outcomes 36-Item Short-Form Health Survey (SF-36) questionnaire was used to assess QoL.ResultsSCD patients who hold a university degree reported positive impacts on the following domains of SF-36: physical role function, vitality, emotional well being, social function, pain reduction, and general health (P = .002, P = .001, P = .001, P = .003, P = .004, and P = .001, respectively). In general, patients with fever, skin redness, swelling, or history of blood transfusion tended to impair the health status of the SF-36. A multivariate analysis revealed that patients with a university degree tended to report high scores of physical role functions, emotional role function, and vitality. Patients with regular exercise tend to increase vitality, social function, general health, and reduce pain. Unemployment tends to lessen vitality and worsen pain. On average, pain, social function, and physical function scores tended to worsen in patients with swelling or history of blood transfusion.ConclusionsThis study highlighted that poor education, fever, skin redness, and swelling were negatively associated with specific components of SF-36. SCD patients with a history of blood transfusion found their QoL poorer, whereas regular exercise tended to improve QoL.

【 授权许可】

CC BY   
© Ahmed et al. 2015