Feasibility and safety of robot-assisted thoracic surgery for lung lobectomy in patients with non-small cell lung cancer: a systematic review and meta-analysis

World Journal of Surgical Oncology

Review

Minghao Chen¹  Lunxu Liu²  Nan Chen²  Shiyou Wei² 

[1] Center for Reproductive Medicine, Guangdong Women and Children Hospital, 510010, Guangzhou, China;Department of Thoracic surgery, West China Hospital, Sichuan University, No. 37, Guoxue Alley, 610041, Chengdu, Sichuan, China;Western China Collaborative Innovation Center for Early Diagnosis and Multidisciplinary Therapy of Lung Cancer, Sichuan University, No. 37, Guoxue Alley, 610041, Chengdu, Sichuan, China;

关键词: Robot-assisted thoracic surgery;    Video-assisted thoracic surgery;    Minimally invasive surgery;    Lung lobectomy;   

DOI  :  10.1186/s12957-017-1168-6

 received in 2016-12-10, accepted in 2017-05-02,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundThe aim of this study is to evaluate the feasibility and safety of robot-assisted thoracic surgery (RATS) lobectomy versus video-assisted thoracic surgery (VATS) for lobectomy in patients with non-small cell lung cancer (NSCLC).MethodsAn electronic search of six electronic databases was performed to identify relevant comparative studies. Meta-analysis was performed by pooling the results of reported incidence of overall morbidity, mortality, prolonged air leak, arrhythmia, and pneumonia between RATS and VATS lobectomy. Subgroup analysis was also conducted based on matched and unmatched cohort studies, if possible. Relative risks (RR) with their 95% confidence intervals (CI) were calculated by means of Revman version 5.3.ResultsTwelve retrospective cohort studies were included, with a total of 60,959 patients. RATS lobectomy significantly reduced the mortality rate when compared with VATS lobectomy (RR = 0.54, 95% CI 0.38–0.77; P = 0.0006), but this was not consistent with the pooled result of six matched studies (RR = 0.12, 95% CI 0.01–1.07; P = 0.06). There was no significant difference in morbidity between the two approaches (RR = 0.97, 95% CI 0.85–1.12; P = 0.70).ConclusionsRATS lobectomy is a feasible and safe technique and can achieve an equivalent short-term surgical efficacy when compared with VATS, but its cost effectiveness also should be taken into consideration.

【 授权许可】

CC BY   
© The Author(s). 2017