Tuberculosis arthritis of the sternoclavicular joint after uncomplicated falciparum malaria: a case report

Annals of Clinical Microbiology and Antimicrobials

Case Report

Daouda Ndiaye¹  Mamadou Alpha Diallo¹  Khadim Diongue¹  Boundia Djiba²  Mouhamed Dieng²  Ngoné Diaba Diack²  Maimouna Sow²  Abdoulaye Pouye²  Baidy Sy Kane²  Hamidou Deme³ 

[1] Laboratoire de Parasitologie-Mycologie, Hôpital Aristide Le Dantec, Université Cheikh Anta Diop de Dakar, BP 5005, Avenue Cheikh Anta Diop, Fann, Dakar, Senegal;Service de Médecine Interne, Hôpital Aristide Le Dantec, Université Cheikh Anta Diop de Dakar, BP 5005, Avenue Cheikh Anta Diop, Fann, Dakar, Senegal;Service d’Imagerie Medicale, Hôpital Aristide Le Dantec, Université Cheikh Anta Diop de Dakar, BP 5005, Avenue Cheikh Anta Diop, Fann, Dakar, Senegal;

关键词: Malaria;    Tuberculosis;    Arthritis;    Immunity;    Co-infection;    Diagnosis;   

DOI  :  10.1186/s12941-017-0219-8

 received in 2017-04-19, accepted in 2017-05-31,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundMalaria and tuberculosis are co-endemic in many developing countries. However their associations are rarely reported. Yet, it has been suggested that a pathological process may link the two diseases.Case presentationA 20-year-old female patient was admitted in the internal medicine service of Aristide Le Dantec Hospital for uncomplicated malaria. She was previously treated for autoimmune hemolytic anaemia using prednisone at 5 mg per day. Clinical examination showed swelling in front of the sternoclavicular joint. She presented with fever and headache. Thick smear from blood revealed trophozoites of P. falciparum at parasite density of 52,300 parasites/μl. The Ziehl–Neelsen stained smear showed the presence of acid-fast bacilli from the fluid puncture of the swelling. Mycobacterium tuberculosis was further isolated in culture. The diagnosis of falciparum malaria co-infection with sternoclavicular tuberculosis was posed. The patient was treated successfully using antimalarial drugs subsequently followed by multidrug antitubercular therapy.ConclusionInteractions between malaria and tuberculosis need to be largely and prospectively investigated and appropriate treatment should be undertaken.

【 授权许可】

CC BY   
© The Author(s) 2017