Prenatal exposure to cooking gas and respiratory health in infants is modified by tobacco smoke exposure and diet in the INMA birth cohort study

Environmental Health

Research

Marisa Estarlich¹  Ferran Ballester²  Ana Esplugues²  David Martinez³  Martine Vrijheid³  Jordi Sunyer⁴  Loreto Santa-Marina⁵  Mikel Basterrechea⁵  Virginia Fuentes-Leonarte⁶  Adonina Tardón⁷  Isolina Riaño⁸ 

[1] CIBER Epidemiología y Salud Pública (CIBERESP), Melchor Fernández Almagro, 3-5, 28029, Madrid, Spain;Center for Public Health Research (CSISP-FISABIO), Avda. de Catalunya, 21, 46020, Valencia, Spain;CIBER Epidemiología y Salud Pública (CIBERESP), Melchor Fernández Almagro, 3-5, 28029, Madrid, Spain;Center for Public Health Research (CSISP-FISABIO), Avda. de Catalunya, 21, 46020, Valencia, Spain;Faculty of Nursing and Chiropody, University of Valencia, Av. Blasco Ibáñez, 13, 46010, Valencia, Spain;CIBER Epidemiología y Salud Pública (CIBERESP), Melchor Fernández Almagro, 3-5, 28029, Madrid, Spain;Center for Research in Environmental Epidemiology (CREAL), Doctor Aiguader, 88, E-08003, Barcelona, Spain;Hospital del Mar Research Institute (IMIM), Doctor Aiguader, 88, 08003, Barcelona, Spain;CIBER Epidemiología y Salud Pública (CIBERESP), Melchor Fernández Almagro, 3-5, 28029, Madrid, Spain;Center for Research in Environmental Epidemiology (CREAL), Doctor Aiguader, 88, E-08003, Barcelona, Spain;Hospital del Mar Research Institute (IMIM), Doctor Aiguader, 88, 08003, Barcelona, Spain;Pompeu Fabra University, Plaça de la Mercè, 10-12, 08002, Barcelona, Spain;CIBER Epidemiología y Salud Pública (CIBERESP), Melchor Fernández Almagro, 3-5, 28029, Madrid, Spain;Public Health Division of Gipuzkoa, Donostia-San Sebastián Basque Government, Avda. de Navarra, 4, 20013, Spain;Health Research Institute, BIODONOSTIA, Hospital Donostia, Pº Doctor Begiristain, s/n 20014, DonostiaBasque Country, Spain;CIBER Epidemiología y Salud Pública (CIBERESP), Melchor Fernández Almagro, 3-5, 28029, Madrid, Spain;Unit of Addictive Disorders, San Marcelino Primary Health Care Center, SAN PIO X, 32ac (C.S. San Marcelino), 46017, Valencia, Spain;CIBER Epidemiología y Salud Pública (CIBERESP), Melchor Fernández Almagro, 3-5, 28029, Madrid, Spain;University of Oviedo, C/ González Besada, nº 13, Oviedo, Asturias, Spain;University of Oviedo, C/ González Besada, nº 13, Oviedo, Asturias, Spain;

关键词: Gas cooking;    Infant;    Wheezing;    Chestiness;    Otitis;    Pregnancy;    Fruit and vegetable consumption;    Tobacco;   

DOI  :  10.1186/1476-069X-12-100

 received in 2013-06-21, accepted in 2013-11-12,  发布年份 2013

来源: Springer

【 摘 要 】

BackgroundStudies that have evaluated the association between exposure to gas appliances emissions at home with respiratory health in children obtained heterogeneous and limited results. The aim of this study is to analyze the association between the use of gas cooking at home during pregnancy and respiratory problems in children during their first year of life.MethodsIn the years 2003 through 2008 pregnant women were enrolled in 4 Spanish areas and visited in different age-points following a common protocol. Outcomes studied (from a questionnaire) were any episode of lower respiratory tract infection (LRTI), wheezing, persistent cough, chestiness and otitis. The association between exposure to gas cooking at home and respiratory outcomes was assessed using logistic regression and adjusting by confounding variables. Some potential effect modifiers (i.e. smoking, fruit and vegetables consumption) were examined.ResultsAmong the 2003 children included in the study, a total of 731 (36.6%) had a LRTI episode, 693 (34.6%) experienced wheezing, 302 (15.5%) a persistent cough, 939 (47.4%) chestiness and 620 (31.2%) had an episode of otitis during their first year of life. Gas cookers were present in 45.5% of homes. Exposure to gas cooking in homes was not associated with respiratory outcomes Odds Ratios (OR) were close to 1 and not statistically significant. However, a positive association was found for otitis among infants whose mothers reported low intakes of fruit and vegetables during pregnancy [OR (95% CI) = 1.38 (1.01-1.9)] and also wheezing and chestiness were associated with gas cookers among those children whose mothers smoked during pregnancy.ConclusionsIn susceptible subjects (those whose mothers smoke and consumed below average fruit and vegetables) we found an association between exposure to gas cooking during pregnancy and risk of wheezing, chestiness and otitis during the first year of life. But more research is needed regarding not only gas cooking and respiratory health but also the possible effect modifier role of diet and tobacco.

【 授权许可】

CC BY   
© Esplugues et al.; licensee BioMed Central Ltd. 2013