Caregiver’s quality of life and its positive impact on symptomatology and quality of life of patients with schizophrenia

Health and Quality of Life Outcomes

Research

Xavier Zendjidjian¹  Marine Alessandrini¹  Laurent Boyer²  David R. Williams³  Alejandra Caqueo-Urízar⁴  Alfonso Urzúa⁵ 

[1] Assistance publique des hôpitaux de Marseille, Hôpital de la Conception, pôle psychiatrie centre, 13005, Marseille, France;Chronic Diseases and Quality of Life – Research Unit, Aix-Marseille University, EA 3279 – Public Health, 13005, Marseille, France;Chronic Diseases and Quality of Life – Research Unit, Aix-Marseille University, EA 3279 – Public Health, 13005, Marseille, France;Department of Social and Behavioral Sciences, Harvard T. H. Chan School of Public Health, 677 Huntington Avenue, 02115-6018, Boston, MA, USA;Department of African and African American Studies, Harvard University, Cambridge, MA, USA;Escuela de Psicología y Filosofía, Universidad de Tarapacá, Avenida 18 de Septiembre 2222, Arica, Chile;Department of Social and Behavioral Sciences, Harvard T. H. Chan School of Public Health, 677 Huntington Avenue, 02115-6018, Boston, MA, USA;Universidad Católica del Norte, Avda. Angamos 0610, Antofagasta, Chile;

关键词: Schizophrenia;    Caregiver;    Quality of life;    Structural equation modeling;   

DOI  :  10.1186/s12955-017-0652-6

 received in 2016-08-09, accepted in 2017-04-06,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundAlthough the quality of life (QoL) experienced by patients with schizophrenia has been recognized, few studies have assessed the relationship between the caregivers’ QoL and patients’ QoL.MethodsThe study included 253 stabilized outpatients with schizophrenia and their caregivers from 3 Mental Health Services in Bolivia (N = 83), Chile (N = 85) and Peru (N = 85). Caregivers’ and patients’ QoL were respectively assessed using two specific QoL questionnaires (S-CGQoL and S-QoL 18). We collected socio-demographic information and clinical data. Multiple linear regressions were performed to determine which variables were associated with patient’s QoL. We tested the following hypothesis using structural equation modeling (SEM): caregivers’ QoL may have an indirect effect on patients’ QoL mediated by their influence of the severity of psychotic symptoms.ResultsIn the multivariate analysis, the caregivers’ QoL was not significantly associated with the patients’ QoL, except for one QoL dimension about relationship with family (Beta = 0.23). Among patients’ characteristics, being a woman and Aymara, having lower educational level, unemployment and severity of symptoms was significantly associated to a lower QoL. The SEM revealed a moderate significant association between caregivers’ QoL and psychotic symptoms severity (path coefficient = −0.32) and a significant association between psychotic symptoms severity and patients QoL (path coefficient = −0.40). The indirect effect of caregivers’ QoL on patients’ QoL was significant (mediated effect coefficient = 0.13).ConclusionImprovement of caregiver’s QoL may have a direct impact on the psychotic symptoms of patients and indirectly on patient’s QoL, confirming the need for ongoing family interventions in these regions.

【 授权许可】

CC BY   
© The Author(s). 2017