期刊论文详细信息
Malaria Journal
Severe malaria in Canada, 2001–2013
Case Study
Chardé Morgan1  Anne E McCarthy1  Chatura Prematunge2  Jennifer Geduld3 
[1] Division of Infectious Diseases, The Ottawa Hospital, 501 Smyth Road, K1H 8L6, Ottawa, ON, Canada;Public Health Ontario, Ottawa, Canada;Travel and Migration Health Division, Public Health Agency of Canada, Ottawa, Canada;
关键词: Severe malaria;    Imported malaria;    Artesunate;    Quinine;   
DOI  :  10.1186/s12936-015-0638-y
 received in 2014-10-06, accepted in 2015-03-03,  发布年份 2015
来源: Springer
PDF
【 摘 要 】

BackgroundImported malaria is the principal, preventable, life-threatening infection among Canadians travelling abroad. The Canadian Malaria Network supplies information and parenteral malaria therapy to healthcare providers treating severe and complicated malaria and gathers surveillance information on these cases.MethodsData were collected on the characteristics, risk factors, and clinical outcomes of severe malaria cases in Canada from June 2001 to December 2013.ResultsThe need for parenteral therapy in Canada has increased in the last decade. The vast majority of cases are reported from Ontario and Quebec and occur among travellers to and from Africa. Regardless of country of birth, all persons originating from endemic and non-endemic countries are at a similar risk of malaria-related complications. Overall use and appropriateness of pre-travel advice and chemoprophylaxis remains low. Most cases result from patient delays in recognizing symptoms and seeking appropriate medical attention. Although some healthcare delays occurred in a select number of cases, the majority of patients were diagnosed quickly and were appropriately treated with parenteral therapy within a few hours of diagnosis.ConclusionsData from the Canadian Malaria Network provide insight into the characteristics of imported severe and complicated malaria infections in Canada. Improved understanding of this population can help target risk reduction strategies and interventions to limit personal susceptibility and healthcare treatment delays.

【 授权许可】

CC BY   
© McCarthy et al.; licensee BioMed Central. 2015

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