Cerebral blood perfusion changes in amputees with myoelectric hands after rehabilitation: a SPECT computer-aided analysis

BMC Neuroscience

Research Article

Xiujuan Zheng¹  Chunlong Zhong²  Panli Li³  Qiufang Liu³  Gang Huang³  Shaoli Song³  Lian Xu³  Yinyan Zhu³  Longwen He⁴  Zhao Mei⁴ 

[1]Department of Automation, School of Electrical Engineering Information, Sichuan University, 610065, Sichuan, China

[2]Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, 160 Pujian Road, 200127, Shanghai, China

[3]Department of Nuclear Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, 160 Pujian Road, 200127, Shanghai, China

[4]Shanghai Rehabilitation and Vocational Training Center for the Disabled, 200127, Shanghai, China

关键词: Cerebral blood flow;    SPECT/CT;    Computed-aided method;    Myoelectric hand;    Rehabilitation;   

DOI  :  10.1186/s12868-016-0294-3

 received in 2016-06-09, accepted in 2016-07-29,  发布年份 2016

来源: Springer

【 摘 要 】

BackgroundRehabilitation, which is essential for amputees with myoelectric hands, can improve the quality of daily life by remodeling the neuron network. In our study, we aim to develop a cerebral blood perfusion (CBF) single-photon emission computed tomography computer-aided (SPECT-CA) detection scheme to automatically locate the brain’s activated regions after rehabilitation.ResultsFive participants without forearms (three male, two female, mean age 51 ± 12.89 years, two missing the right side, and three missing the left side) were included in our study. In the clinical assessment, all of the participants received higher scores after training. The results of the SPM analysis indicated that CBF in the precentral gyrus, postcentral gyrus, frontal lobe, temporal lobe and cerebellum was significantly different among the five participants (P < 0.05). Moreover, SPECT-CA showed that the activated brain areas mainly included the precentral gyrus, postcentral gyrus, cerebellum and extensive cerebral cortex.ConclusionOur study demonstrated that the CBF SPECT-CA method can detect the brain blood perfusion changes induced by rehabilitation with high sensitivity and accuracy. This method has great potential for locating the remodeled neuron regions of amputees with myoelectric hands after rehabilitation.

【 授权许可】

CC BY   
© The Author(s) 2016