Development and validation of a new Arrhythmia-Specific questionnaire in Tachycardia and Arrhythmia (ASTA) with focus on symptom burden

Health and Quality of Life Outcomes

Research

Anna Stromberg¹  Ulla Walfridsson²  Kristofer Arestedt³ 

[1] Division of Nursing Science, Department of Medicine and Health Sciences, Linkping University, Department of Cardiology UHL, County Council of stergtland, Linkping, Sweden;Division of Nursing Science, Department of Medicine and Health Sciences, Linkping University, Department of Cardiology UHL, County Council of stergtland, Linkping, Sweden;Department of Cardiology, University Hospital, SE 581 85, Linkping, Sweden;School of Health and Caring Sciences, Faculty of Health, Social Work and Behavioural Sciences, Linnaeus University Kalmar and Department of Medical and Health Sciences, Division of Nursing Science, Linkping University, Linkoping, Sweden;

关键词: Arrhythmias;    Symptom burden;    Disease-specific questionnaire;    Questionnaire development;    Validation;   

DOI  :  10.1186/1477-7525-10-44

 received in 2011-07-25, accepted in 2012-04-30,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundArrhythmias can appear with a variety of symptoms, all from vague to pronounced and handicapping symptoms. Therefore, patient-reported outcomes (PROs) concerning symptom burden are important to assess and take into consideration in the care and treatment of patients with arrhythmias. The main purpose was to develop and validate a disease-specific questionnaire evaluating symptom burden in patients with different forms of arrhythmias.MethodsA literature review was conducted and arrhythmia patients were interviewed. Identified symptoms were evaluated by an expert panel consisting of cardiologists and nurses working daily with arrhythmia patients. SF-36 and Symptoms Checklist (SCL) were used in the validation of the new questionnaire Arrhythmia-Specific questionnaire in Tachycardia and Arrhythmia (ASTA).Homogeneity was evaluated with Spearman´s correlations and Cronbach´s alpha coefficient (α) was used to evaluate internal consistency. Construct validity was evaluated using item-total correlations and convergent and discriminant validity. For this, Spearman´s correlations were calculated between the ASTA symptom scale, SCL and SF-36. Concurrent validity was validated by Spearman´s correlations between the ASTA symptom scale and SCL.ResultsThe correlations between the different items in the ASTA symptom scale showed generally sufficient homogeneity. Cronbach´s coefficient was found to be satisfactory (α = 0.80; lower bound 95 % CI for α = 0.76). Construct validity was supported by item-total correlations where all items in the symptom scale were sufficiently correlated (≥0.3). Convergent and discriminant validity was supported by the higher correlations to the arrhythmia-specific SCL compared to the generic SF-36. Concurrent validity was evaluated and there were sufficiently, but not extremely strong correlations found between the ASTA symptom scale and SCL.ConclusionsThe nine items of the ASTA symptom scale were found to have good psychometric properties in patients with different forms of arrhythmias. Arrhythmia patients suffer from both frequent and disabling symptoms. The validated ASTA questionnaire can be an important contribution to PROs regarding symptom burden in arrhythmia patients.

【 授权许可】

CC BY   
© Walfridsson et al.; licensee BioMed Central Ltd. 2012