Validation of Acromegaly Quality of Life Questionnaire (AcroQoL) for the Iranian population

BMC Psychology

Leyla Bahadorizadeh¹  Shirin Mohamadzadeh²  Mohammad E. Khamseh³  Nahid Hashemi-Madani³  Afsaneh Dehnad⁴  Mina Danaei⁵ 

[1] Antimicrobial Resistance Research Center, Institute of Immunology and Infectious Disease, Iran University of Medical Sciences;Department of English Language, Alzahra University;Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences (IUMS);School of Health Management and Information Sciences, Iran University of Medical Sciences;Social Determinants of Health Research Center, Institute of Futures Studies in Health, Kerman University of Medical Sciences;

关键词: Acromegaly;    Quality of life;    Disease-specific questionnaire;   

DOI  :  10.1186/s40359-022-00781-0

来源: DOAJ

【 摘 要 】

Abstract Background Acromegaly is a chronic disease significantly affects the physical, emotional, and health-related aspects of patients' life. This study aimed to validate the Acromegaly Quality of Life Questionnaire (AcroQoL) for the Persian-speaking population. Methods This cross-sectional study recruited 73 Iranian patients with a confirmed diagnosis of acromegaly. The content validity of the scales was evaluated by an expert panel of eight endocrinologists applying content validity index (CVI) and content validity ratio (CVR). Construct validity was assessed by using confirmatory factor analysis. Internal consistency was assessed on the basis of Cronbach’s alpha, and a goodness-of-fit (GoF) index was calculated to display whether the model fitted the data. Results CVI and CVR yielded values of 0.85 and 0.80, respectively (Acceptable CVI: > 0.78 and CVR: > 0.75). The average variances extracted (AVE) from physical and psychological dimensions were 0.520 and 0.462, respectively, exceeding the minimum criterion of 0.40. Cronbach’s alpha for physical and psychological dimensions equaled 0.868 and 0.866, respectively, indicating the adequate internal consistency of multiple items for each construct. The subscales’ R square and path coefficient were greater than the recommended threshold as 0.75 (physical dimension: 0.778, psychological dimension: 0.873), demonstrating the suitability of this criterion. Finally, the GoF value of 0.29 indicated the model's moderate fit. Conclusions The findings revealed that the Persian version of AcroQoL is of adequate validity and reliability for evaluating the quality of life of Iranian people with acromegaly.

【 授权许可】

Unknown