Development of an item bank for the EORTC Role Functioning Computer Adaptive Test (EORTC RF-CAT)

Health and Quality of Life Outcomes

Research

Eva-Maria Gamper¹  Johannes M. Giesinger²  Bernhard Holzner³  Anne Oberguggenberger³  Georg Kemmler³  Susanne Singer⁴  Mogens Groenvold⁵  Teresa Young⁶  Neil Aaronson⁷  Anna Costantini⁸  Morten Aa Petersen⁹ 

[1]Department for Psychiatry and Psychotherapy and Department for Nuclear Medicine, Medical University of Innsbruck, Anichstraße 35, 6020, Innsbruck, Austria

[2]Department for Psychiatry, Psychotherapy and Psychosomatic Medicine, Medical University of Innsbruck, Anichstraßé 35, 6020, Innsbruck, Austria

[3]Department for Psychiatry and Psychotherapy, Medical University of Innsbruck, Anichstraße 35, 6020, Innsbruck, Austria

[4]Department for Psychiatry and Psychotherapy, Medical University of Innsbruck, Anichstraße 35, 6020, Innsbruck, Austria

[5]Department for Psychiatry, Psychotherapy and Psychosomatic Medicine, Medical University of Innsbruck, Anichstraßé 35, 6020, Innsbruck, Austria

[6]Department of Medical Biostatistics, Epidemiology, and Informatics, University of Mainz, Saarstraße 21, 55122, Mainz, Germany

[7]Department of Public Health, Institute of Health Services Research, University of Copenhagen, Norregade 10, 1165, Copenhagen, Denmark

[8]The Research Unit, Department of Palliative Medicine, Bispebjerg Hospital, Bispebjerg Bakke 23, 2400, Copenhagen, Denmark

[9]Mount Vernon Cancer Centre, Lynda Jackson Macmillan Centre, Northwood, HA6 2RN, Middlesex, UK

[10]Netherlands Cancer Institute, Psychosocial Research and Epidemiology, Plesmanlaan 121, 1066 CX, Amsterdam, Netherlands

[11]Psychoncology Unit, Sant’Andrea Hospital Sapienza University of Rome, Via di Grottarossa 1035, 00189, Rome, Italy

[12]The Research Unit, Department of Palliative Medicine, Bispebjerg Hospital, Bispebjerg Bakke 23, 2400, Copenhagen, Denmark

关键词: Cancer;    Oncology;    Health related quality of life;    Role functioning;    QLQ-C30;    Computer-adaptive test;   

DOI  :  10.1186/s12955-016-0475-x

 received in 2015-06-09, accepted in 2016-04-28,  发布年份 2016

来源: Springer

【 摘 要 】

BackgroundRole functioning (RF) as a core construct of health-related quality of life (HRQOL) comprises aspects of occupational and social roles relevant for patients in all treatment phases as well as for survivors. The objective of the current study was to improve its assessment by developing a computer-adaptive test (CAT) for RF. This was part of a larger project whose objective is to develop a CAT version of the EORTC QLQ-C30 which is one of the most widely used HRQOL instruments in oncology.MethodsIn accordance with EORTC guidelines, the development of the RF-CAT comprised four phases. Phase I involved the conceptualization of RF. In Phase II, a provisional list of items was defined and revised by experts in the field. In phase III, feedback was obtained from cancer patients in various countries. Phase IV comprised field testing in an international sample, calibration of the item bank, and evaluation of the psychometric performance of the RF-CAT.ResultsPhases I-III yielded a list of 12 items eligible for phase IV field-testing. The field-testing sample included 1,023 patients from Austria, Denmark, Italy, and the UK. Psychometric evaluation and item response theory analyses yielded 10 items with good psychometric properties. The resulting item bank exhibits excellent reliability (mean reliability = 0.85, median = 0.95). Using the RF-CAT may allow sample size savings from 11 % up to 50 % compared to using the QLQ-C30 RF scale.ConclusionsThe RF-CAT item bank improves the precision and efficiency with which RF can be assessed, promoting its integration into oncology research and clinical practice.

【 授权许可】

CC BY   
© Gamper et al. 2016