History of malaria research and its contribution to the malaria control success in Suriname: a review

Malaria Journal

Review

Stephen GS Vreden¹  Florence JV Breeveld²  Martin P Grobusch³ 

[1] Academisch Ziekenhuis Paramaribo, Paramaribo, Suriname;Center for Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Division of Internal Medicine, Academic Medical Center, University of Amsterdam, PO Box 22660, Meibergdreef 9, 1100 DE, Amsterdam, The Netherlands;Center for Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Division of Internal Medicine, Academic Medical Center, University of Amsterdam, PO Box 22660, Meibergdreef 9, 1100 DE, Amsterdam, The Netherlands;Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany;

关键词: Artemisinin-based combination therapy;    Control;    Elimination;    Eradication;    Gold mining;    Malaria;    Resistance;    Suriname;   

DOI  :  10.1186/1475-2875-11-95

 received in 2012-01-03, accepted in 2012-03-29,  发布年份 2012

来源: Springer

【 摘 要 】

Suriname has cleared malaria from its capital city and coastal areas mainly through the successful use of chloroquine and DDT (dichloro-diphenyl-trichloroethane) during the Global Malaria Eradication programme that started in 1955. Nonetheless, malaria transmission rates remained high in the interior of the country for a long time. An impressive decline in malaria cases was achieved in the past few years, from 14,403 registered cases in 2003 to 1,371 in 2009. The introduction of artemisinin-based combination therapy (ACT) in 2004 has further fuelled the decrease in the number of infections with Plasmodium falciparum. The only population group still heavily burdened with malaria is gold mining industry workers. Interestingly, an important part of malaria cases diagnosed and treated in Suriname originate from border regions. Therefore, practical initiatives of combined efforts between neighbouring countries must be scaled up in order to effectively attack these specific areas. Furthermore, it is of vital importance to keep investing into the malaria control programme and public awareness campaigns. Especially the correct use of ACT must be promoted in order to prevent the emergence of resistance. However, effective preventive measures and adequate therapeutic options are on their own not enough to control, let alone eliminate malaria. Changing personal and social behaviour of people is particularly difficult, but crucial in making the current success sustainable. With this in mind, research on successfully implemented interventions, focusing on behavioural modifications and methods of measuring their effectiveness, must be expanded.

【 授权许可】

Unknown   
© Breeveld et al; licensee BioMed Central Ltd. 2012. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.