A blended module (STAIRS) to promote functional and personal recovery in patients with a major depressive disorder in remission: study protocol of a concurrent mixed methods randomized controlled trial

BMC Psychiatry

Study Protocol

Klaas J. Wardenaar¹  Antoinette D. I. van Asselt²  Manna A. Alma³  Robert A. Schoevers⁴  David Wedema⁵  Eliza L. Korevaar⁵ 

[1] Department of Behavioural and Social Sciences, University of Groningen, Groningen, The Netherlands;Department of Epidemiology, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands;Department of Health Sciences, Applied Health Research, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands;Department of Psychiatry, Research School of Behavioural and Cognitive Neurosciences (BCN), University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands;Research and Innovation Centre for Rehabilitation, Hanze University of Applied Sciences, Groningen, The Netherlands;

关键词: Functional recovery;    Personal recovery;    Depression;    Peer group;    Expert by experience;    Blended care;    Social support;    Recovery-oriented care;   

DOI  :  10.1186/s12888-023-05213-w

 received in 2023-09-18, accepted in 2023-09-22,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundDespite the availability of a wide variety of evidence-based treatments for major depressive disorder (MDD), many patients still experience impairments in their lives after remission. Programs are needed that effectively support patients in coping with these impairments. The program Storytelling and Training to Advance Individual Recovery Skills (STAIRS) was developed to address this need and combines the use of peer contact, expert-by-experience guidance, family support and professional blended care. The aim of the planned study is (1) to assess the efficacy of the STAIRS program in patients with remitted MDD, (2) to investigate patients’ subjective experiences with STAIRS, and (3) to evaluate the program’s cost-effectiveness.MethodsA concurrent mixed-methods randomized controlled trial design will be used. Patients aged between 18 and 65 years with remitted MDD (N = 140) will be randomized to either a group receiving care as usual (CAU) + the STAIRS-program or a control group receiving CAU + some basic psychoeducation. Quantitative efficacy data on functional and personal recovery and associated aspects will be collected using self-report questionnaires at the start of the intervention, immediately following the intervention, and at the six-month follow-up. Insights into patients’ experiences on perceived effects and the way in which different program elements contribute to this effect, as well as the usability and acceptability of the program, will be gained by conducting qualitative interviews with patients from the experimental group, who are selected using maximum variation sampling. Finally, data on healthcare resource use, productivity loss and quality of life will be collected and analysed to assess the cost-effectiveness and cost-utility of the STAIRS-program.DiscussionWell-designed recovery-oriented programs for patients suffering from MDD are scarce. If efficacy and cost-effectiveness are demonstrated with this study and patients experience the STAIRS program as usable and acceptable, this program can be a valuable addition to CAU. The qualitative interviews may give insights into what works for whom, which can be used to promote implementation.Trial registrationThis trial was registered at ClinicalTrials.gov on 1 July 2021, registration number NCT05440812.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

【 图 表 】

Fig. 2

Fig. 1