Quality of life of patients after retropubic prostatectomy - Pre- and postoperative scores of the EORTC QLQ-C30 and QLQ-PR25

Health and Quality of Life Outcomes

Research

Tanja Döring¹  Andreas Gesenberg¹  Cornelia Möhring¹  Peter Bach¹  Mark Goepel¹ 

[1] Department of Urology of Klinikum Niederberg Velbert, Academic Hospital, University of Duisburg-Essen, Germany;

关键词: Erectile Dysfunction;    Radical Prostatectomy;    Symptom Score;    Radical Retropubic Prostatectomy;    Global Health Status;   

DOI  :  10.1186/1477-7525-9-93

 received in 2010-10-28, accepted in 2011-11-02,  发布年份 2011

来源: Springer

【 摘 要 】

BackgroundPatients with newly diagnosed early stage prostate cancer (PCa) face a difficult choice of different treatment options with curative intention. They must consider both goals of optimising quantity and quality of life. The quality of life (QoL) is a psychometric outcome which is measured using validated questionnaires. Only few data are published concerning pre - and postoperative QoL.MethodsThis study investigated pre perative QoL of 185 patients who consecutively underwent open radical retropubic prostatectomy for organ-confined PCa to postoperative QoL of another 185 patients. The EORTC QLQ-C30, EORTC QLQPR25 module and 24 h ICS pad test were used (mean follow-up 28.6 months).ResultsThe examined symptom scores of the EORTC QLQ-PR25 were on lowest level. In the dyspnoea symptom score differences of age emerged: the amount of patients who are short of breath rose significantly in older patients after surgery (p < 0.05 paired, two-tailed student's t-test).. Lastly, the urinary symptom score was found postal-therapeutically low; this fact was age independent. The results of sexual symptom score need to be taken into consideration, since prostatectomy resulted in a significant reduction of sexual activity independent of age. All functioning scales postoperatively reached high values without significant changes (p > 0.05 student's t-test ), which implies a high QoL after surgery. A reliable and satisfying status of continence was found in our patients after retropubic prostatectomy. A high rate of patients (89.2%) would choose retropubic prostatectomy again.ConclusionRetropubic prostatectomy represents a reliable and accepted procedure in the treatment of organ-confined PCa. For the first time it could be shown that patients` QoL remained on a high level after retropubic prostatectomy. Nevertheless, the primary avoidance or postoperative therapy of erectile dysfunction should be in the focus of surgeons.

【 授权许可】

CC BY   
© Bach et al; licensee BioMed Central Ltd. 2011