Effects of exercise training on patients with lung cancer who underwent lung resection: a meta-analysis

World Journal of Surgical Oncology

Research

Jie Li¹  Hua Yu¹  Nan-Nan Guo¹  Hai-Rong Jin¹  Peng Wang²  Guo-Gang Xu³ 

[1] Department of Thoracic Surgery, Chinese PLA General Hospital, 100853, Beijing, China;Nanlou Medical Oncology Department, Chinese PLA General Hospital, 100853, Beijing, China;Nanlou Respiratory Diseases Department, Chinese PLA General Hospital, No. 28 Fuxing Road, Haidian District, 100853, Beijing, China;

关键词: Lung cancer;    Exercise;    Quality of life;    Meta-analysis;   

DOI  :  10.1186/s12957-017-1233-1

 received in 2017-04-25, accepted in 2017-08-13,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundThe efficacy of exercise training in patients with lung cancer after lung resection has not been well established yet. Therefore, we performed a meta-analysis to investigate the efficiency of exercise training in patients with lung cancer after lung resection.MethodsSeveral databases were searched for eligible randomised controlled trials (RCTs). The primary outcome was quality of life, and the secondary outcomes included 6-min walk distance (6MWD), forced expiratory volume in 1 s (FEV1) and postoperative complications (POCs). Weighted mean differences (WMDs) and relative risks (RRs) with 95% confidence intervals (CIs) were calculated by random-effects model.ResultsSix RCTs involving 438 patients were enrolled in this meta-analysis. The pooled WMDs of the scores were 2.41 (95% CI = −5.20 to 10.02; P = 0.54) and −0.46 (95% CI = −20.52 to 19.61; P = 0.96) for the physical and mental components of the 36-item short-form scale, respectively. The pooled WMDs were 23.50 m (95% CI = −22.04 to 69.03; P = 0.31) for 6MWD and 0.03 L (95% CI = −0.19 to 0.26; P = 0.76) for FEV1. Finally, the pooled RRs were 0.79 (95% CI = 0.41 to 1.53; P = 0.49) for POCs.ConclusionsInsufficient evidence is available to support the efficacy of exercise training in patients with lung cancer after lung resection. Further studies must confirm our findings and investigate the long-term effects of exercise training on patients with lung cancer following lung resection.

【 授权许可】

CC BY   
© The Author(s). 2017