Determinants of glycemic control in female diabetic patients: a study from Iran

Lipids in Health and Disease

Research

Hamid Agha-Alinejad¹  Zeinab Ghazanfari²  Fazlollah Ghofranipour²  Shamsaddin Niknami²  Ali Montazeri³  Bagher Larijani⁴ 

[1] Department of Exercise Physiology, Islamic Azad University, Central Tehran Branch, Tehran, Iran;Department of Health Education, Tarbiat Modares University, Tehran, Iran;Department of Mental Health, Institute for Health Sciences Research, ACECR, Tehran, Iran;Endocrine and Metabolism Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran;

关键词: Body Mass Index;    Waist Circumference;    Glycemic Control;    HbA1c Level;    Visceral Adipose Tissue;   

DOI  :  10.1186/1476-511X-9-83

 received in 2010-07-03, accepted in 2010-08-11,  发布年份 2010

来源: Springer

【 摘 要 】

BackgroundSince microvascular and macrovascular complications are reduced through strict glycemic control, this study carried out to identify the factors that affect glycemic control.MethodsA cross-sectional design was carried out to examine the role of demographic, anthropometric, clinical and other relevant characteristics in a sample of 103 female diabetic patients in Tehran, Iran. Personal interviews were conducted to collect data. Then blood sampling collected and the patients were divided into two outcome groups (controlled and uncontrolled diabetes). The groups were compared on the basis of their characteristics using both univariate and multivariate analyses.ResultsIn all 103 patients were entered into the study. The mean age of patients was 46.38 (SD = 11.42) years. Overall, the mean value of HbA1c for the whole sample was 7.5 (SD = 2.35) and 56.3% had HbA1c ≥ 7%. The findings obtained from univariate analysis revealed that there were no significant differences between controlled and uncontrolled patients. However, in multivariate analysis the waist circumference was found to be a significant predictor of increased level of HbA1c (OR = 1.04, 95% CI = 1-1.08, P = 0.04).ConclusionsThe findings suggest that increased level of HbA1c is associated with waist circumference that is a modifiable factor. It seems that physical activity might be a solution to overcome this health problem. A larger study to identify other factors also is recommended.

【 授权许可】

Unknown   
© Ghazanfari et al; licensee BioMed Central Ltd. 2010. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.