Magnetic resonance enterography in pregnant women with Crohn’s disease: case series and literature review

BMC Gastroenterology

Research Article

Myriam D Stern¹  Marianne Michal Amitai¹  Sarah Apter¹  Shomron Ben-Horin²  Uri Kopylov² 

[1] Department of Diagnostic Imaging, Sheba Medical Center, Ramat Gan, Israel;Department of Gastroenterology, Sheba Medical Center, Ramat Gan, Israel;

关键词: Crohn’s disease;    Pregnancy;    Magnetic resonance enterography;    MRI;   

DOI  :  10.1186/1471-230X-14-146

 received in 2014-03-11, accepted in 2014-08-13,  发布年份 2014

来源: Springer

【 摘 要 】

BackgroundEvaluation of pregnant women with known or suspected Crohn’s disease (CD) remains a challenge. Magnetic Resonance Enterography (MRE) is a promising diagnostic tool in these patients; however, the clinical data on MRE utilization in pregnancy is scarce. The aim of the study was to describe the experience with MRE in pregnant CD patients in a tertiary referral center.MethodsWe retrospectively reviewed MRE studies performed in pregnant women with known or suspected CD that were performed between January 2007 and November 2012. Imaging findings, clinical management and outcome were extracted from patient’s file and electronic records. Image quality was evaluated.ResultsTen studies of 9 patients were included. MRE protocol was modified to maximize maternal and fetal safety, and intravenous gadolinium was not used. In 7 patients, CD diagnosis was previously established; six were admitted with clinical symptoms consistent with CD exacerbation, and an additional patient with a recurrent groin abscess without apparent luminal symptoms. In all seven patients, imaging features consistent with active CD were detected; new penetrating complications were detected in 4 patients. Two patients underwent MRE for suspected CD which was not comforted by study results. The clinical management was significantly impacted by MRE results in all positive cases. The image quality of the fast MRE sequences obtained without gadolinium was satisfactory and allowed meaningful interpretation.ConclusionMRE with an adapted protocol for pregnancy is a reliable imaging modality to manage in pregnant women with known or suspected CD.

【 授权许可】

Unknown   
© Stern et al.; licensee BioMed Central Ltd. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.