A novel technique to quantify the instantaneous mitral regurgitant rate

Journal of Cardiovascular Magnetic Resonance

Research

Steven D Wolff¹  Farooq A Chaudhry²  Linda Gillam³  Naganath Thota⁴  Srinivasa Gurram⁴  Seth Uretsky⁴  Harikrishna Ponnam⁴  Sri Lakshmi Kala Bonda⁴  Eric Bader⁴  Randy Cohen⁴  Azhar Supariwala⁴ 

[1] Carnegie Hill Radiology, New York, NY, USA;Department of Cardiology, Mount Sinai School of Medicine, New York, NY, USA;Department of Cardiovascular Medicine, Morristown Medical Center, Morristown, NJ, USA;Department of Medicine, Division of Cardiology, St. Luke’s-Roosevelt Hospital Center, 1111 Amsterdam Ave, Cardiology 3rd Floor, 10025, New York, NY, USA;

关键词: Mitral regurgitation;    Cardiovascular magnetic resonance;    Echocardiography;    Temporal variation;   

DOI  :  10.1186/1532-429X-15-74

 received in 2013-05-08, accepted in 2013-08-22,  发布年份 2013

来源: Springer

【 摘 要 】

BackgroundThe systolic variation of mitral regurgitation (MR) is a pitfall in its quantification. Current recommendations advocate using quantitative echocardiographic techniques that account for this systolic variation. While prior studies have qualitatively described patterns of systolic variation no study has quantified this variation.MethodsThis study includes 41 patients who underwent cardiovascular magnetic resonance (CMR) evaluation for the assessment of MR. Systole was divided into 3 equal parts: early, mid, and late. The MR jets were categorized as holosystolc, early, or late based on the portions of systole the jet was visible. The aortic flow and left ventricular stroke volume (LVSV) acquired by CMR were plotted against time. The instantaneous regurgitant rate was calculated for each third of systole as the difference between the LVSV and the aortic flow.ResultsThe regurgitant rate varied widely with a 1.9-fold, 3.4-fold, and 1.6-fold difference between the lowest and highest rate in patients with early, late, and holosystolic jets respectively. There was overlap of peak regurgitant rates among patients with mild, moderate and severe MR. The greatest variation of regurgitant rate was seen among patients with mild MR.ConclusionCMR can quantify the systolic temporal variation of MR. There is significant variation of the mitral regurgitant rate even among patients with holosystolic MR jets. These findings highlight the need to use quantitative measures of MR severity that take into consideration the temporal variation of MR.

【 授权许可】

CC BY   
© Uretsky et al.; licensee BioMed Central Ltd. 2013