A novel technique to quantify the instantaneous mitral regurgitant rate

Journal of Cardiovascular Magnetic Resonance

Steven D Wolff¹  Azhar Supariwala³  Randy Cohen³  Naganath Thota³  Eric Bader³  Harikrishna Ponnam³  Sri Lakshmi Kala Bonda³  Srinivasa Gurram³  Linda Gillam²  Farooq A Chaudhry⁴  Seth Uretsky³ 

[1] Carnegie Hill Radiology, New York, NY USA;Department of Cardiovascular Medicine, Morristown Medical Center, Morristown, NJ USA;Department of Medicine, Division of Cardiology, St. Luke’s-Roosevelt Hospital Center, 1111 Amsterdam Ave, Cardiology 3rd Floor, New York, NY 10025, USA;Department of Cardiology, Mount Sinai School of Medicine, New York, NY USA

关键词: Temporal variation;    Echocardiography;    Cardiovascular magnetic resonance;    Mitral regurgitation;   

Others  :  805522
DOI  :  10.1186/1532-429X-15-74

 received in 2013-05-08, accepted in 2013-08-22,  发布年份 2013

【 摘 要 】

Background

The systolic variation of mitral regurgitation (MR) is a pitfall in its quantification. Current recommendations advocate using quantitative echocardiographic techniques that account for this systolic variation. While prior studies have qualitatively described patterns of systolic variation no study has quantified this variation.

Methods

This study includes 41 patients who underwent cardiovascular magnetic resonance (CMR) evaluation for the assessment of MR. Systole was divided into 3 equal parts: early, mid, and late. The MR jets were categorized as holosystolc, early, or late based on the portions of systole the jet was visible. The aortic flow and left ventricular stroke volume (LVSV) acquired by CMR were plotted against time. The instantaneous regurgitant rate was calculated for each third of systole as the difference between the LVSV and the aortic flow.

Results

The regurgitant rate varied widely with a 1.9-fold, 3.4-fold, and 1.6-fold difference between the lowest and highest rate in patients with early, late, and holosystolic jets respectively. There was overlap of peak regurgitant rates among patients with mild, moderate and severe MR. The greatest variation of regurgitant rate was seen among patients with mild MR.

Conclusion

CMR can quantify the systolic temporal variation of MR. There is significant variation of the mitral regurgitant rate even among patients with holosystolic MR jets. These findings highlight the need to use quantitative measures of MR severity that take into consideration the temporal variation of MR.

【 授权许可】

   
2013 Uretsky et al.; licensee BioMed Central Ltd.

【 图 表 】

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