Evaluation of left ventricular diastolic function by fractional area change using cine cardiovascular magnetic resonance: a feasibility study

Journal of Cardiovascular Magnetic Resonance

Research

Makoto Watanabe¹  Tamio Nakajima¹  Shinichi Fujimoto²  Tomoya Nakano³  Satoshi Okayama³  Shiro Uemura³  Satoshi Somekawa³  Yoshihiko Saito³ 

[1] Department of Cardiology, Hirai Hospital, Nara, Japan;Education Development Center, Nara Medical University, Nara, Japan;First Department of Internal Medicine, Nara Medical University, Nara, Japan;

关键词: Cine;    Diastolic function;    Relaxation;    Pseudonormal;    Echocardiography;    Color kinesis;   

DOI  :  10.1186/1532-429X-15-87

 received in 2013-07-02, accepted in 2013-09-17,  发布年份 2013

来源: Springer

【 摘 要 】

BackgroundEvaluation of left ventricular (LV) diastolic function is essential for the management of heart failure. We verified whether LV diastolic function could be evaluated by measuring the fractional area change (FAC) using cine cardiovascular magnetic resonance (CMR).MethodsWe collected clinical data from 59 patients who underwent echocardiography and cine CMR. Normal, impaired relaxation, pseudonormal, and restrictive LV filling were observed in 15, 28, 11, and 5 patients, respectively. We calculated FAC during the first 30% of diastole (diastolic-index%) in the short-axis view, by tracing the contours on only three MR cine images.ResultsThe diastolic index was significantly lower (p < 0.0001) in patients with impaired relaxation (32.4 ± 7.5), pseudonormal filling (25.4 ± 5.6), and restrictive filling (9.5 ± 1.5) compared to those with normal diastolic function (67.7 ± 10.8), and the index decreased significantly with worsening of diastolic dysfunction. The diastolic index correlated positively with early diastolic mitral annular velocity measured by tissue Doppler imaging (r = 0.75, p < 0.0001), respectively.ConclusionsMeasurement of FAC can be useful for the evaluation of LV diastolic function using cine CMR.

【 授权许可】

CC BY   
© Okayama et al.; licensee BioMed Central Ltd. 2013