Evaluation of left ventricular diastolic function by fractional area change using cine cardiovascular magnetic resonance: a feasibility study

Journal of Cardiovascular Magnetic Resonance

Yoshihiko Saito¹  Tamio Nakajima²  Makoto Watanabe²  Satoshi Somekawa¹  Shinichi Fujimoto³  Shiro Uemura¹  Tomoya Nakano¹  Satoshi Okayama¹ 

[1] First Department of Internal Medicine, Nara Medical University, Nara, Japan;Department of Cardiology, Hirai Hospital, Nara, Japan;Education Development Center, Nara Medical University, Nara, Japan

关键词: Color kinesis;    Echocardiography;    Pseudonormal;    Relaxation;    Diastolic function;    Cine;   

Others  :  803977
DOI  :  10.1186/1532-429X-15-87

 received in 2013-07-02, accepted in 2013-09-17,  发布年份 2013

【 摘 要 】

Background

Evaluation of left ventricular (LV) diastolic function is essential for the management of heart failure. We verified whether LV diastolic function could be evaluated by measuring the fractional area change (FAC) using cine cardiovascular magnetic resonance (CMR).

Methods

We collected clinical data from 59 patients who underwent echocardiography and cine CMR. Normal, impaired relaxation, pseudonormal, and restrictive LV filling were observed in 15, 28, 11, and 5 patients, respectively. We calculated FAC during the first 30% of diastole (diastolic-index%) in the short-axis view, by tracing the contours on only three MR cine images.

Results

The diastolic index was significantly lower (p < 0.0001) in patients with impaired relaxation (32.4 ± 7.5), pseudonormal filling (25.4 ± 5.6), and restrictive filling (9.5 ± 1.5) compared to those with normal diastolic function (67.7 ± 10.8), and the index decreased significantly with worsening of diastolic dysfunction. The diastolic index correlated positively with early diastolic mitral annular velocity measured by tissue Doppler imaging (r = 0.75, p < 0.0001), respectively.

Conclusions

Measurement of FAC can be useful for the evaluation of LV diastolic function using cine CMR.

【 授权许可】

   
2013 Okayama et al.; licensee BioMed Central Ltd.

【 图 表 】

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