Influenza A/H1N1 septic shock in a patient with systemic lupus erythematosus. A case report

BMC Infectious Diseases

Case Report

Panagiota Boura¹  Konstantinos Tselios¹  Alexandros Sarantopoulos¹  Ritsa Tsioka²  Eleni Mouloudi² 

[1] Clinical Immunology Unit, 2nd Department of Internal Medicine, Hippokration General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece;Intensive Care Unit, Hippokration General Hospital, Thessaloniki, Greece;

关键词: Influenza A/H1N1;    systemic lupus erythematosus;    septic shock;   

DOI  :  10.1186/1471-2334-11-358

 received in 2011-07-22, accepted in 2011-12-29,  发布年份 2011

来源: Springer

【 摘 要 】

BackgroundImmunocompromised patients, such as systemic lupus erythematosus (SLE) sufferers have an increased risk of mortality, following influenza infection. In the recent pandemic, influenza A H1NI virus caused 18449 deaths, mainly because of adult respiratory distress syndrome or bacterial co-infections.Case PresentationIn this case report, an SLE patient with viral-induced septic shock, without overt pulmonary involvement, is discussed. The patient was administered oseltamivir and supportive treatment, including wide-spectrum antibiotics, vasopressors and steroids, according to the guidelines proposed for bacterial sepsis and septic shock. She finally survived and experienced a lupus flare soon after intensive care unit (ICU) discharge.ConclusionsTo our knowledge, this is the first case to report severe septic shock from influenza A/H1N1 virus, without overt pulmonary involvement.

【 授权许可】

Unknown   
© Tselios et al; licensee BioMed Central Ltd. 2011. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.