Influenza A/H1N1 septic shock in a patient with systemic lupus erythematosus. A case report

BMC Infectious Diseases

Panagiota Boura¹  Eleni Mouloudi²  Alexandros Sarantopoulos¹  Ritsa Tsioka²  Konstantinos Tselios¹ 

[1] Clinical Immunology Unit, 2nd Department of Internal Medicine, Hippokration General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece;Intensive Care Unit, Hippokration General Hospital, Thessaloniki, Greece

关键词: septic shock;    systemic lupus erythematosus;    Influenza A/H1N1;   

Others  :  1175491
DOI  :  10.1186/1471-2334-11-358

 received in 2011-07-22, accepted in 2011-12-29,  发布年份 2011

【 摘 要 】

Background

Immunocompromised patients, such as systemic lupus erythematosus (SLE) sufferers have an increased risk of mortality, following influenza infection. In the recent pandemic, influenza A H1NI virus caused 18449 deaths, mainly because of adult respiratory distress syndrome or bacterial co-infections.

Case Presentation

In this case report, an SLE patient with viral-induced septic shock, without overt pulmonary involvement, is discussed. The patient was administered oseltamivir and supportive treatment, including wide-spectrum antibiotics, vasopressors and steroids, according to the guidelines proposed for bacterial sepsis and septic shock. She finally survived and experienced a lupus flare soon after intensive care unit (ICU) discharge.

Conclusions

To our knowledge, this is the first case to report severe septic shock from influenza A/H1N1 virus, without overt pulmonary involvement.

【 授权许可】

   
2011 Tselios et al; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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