Association between socioeconomic status and metabolic control and diabetes complications: a cross-sectional nationwide study in Chinese adults with type 2 diabetes mellitus

Cardiovascular Diabetology

Original Investigation

Dayi Hu¹  Linong Ji²  Yuxin Huang³  Xiaoming Tao³  Suyuan Jiang³  Qiang Feng³  Cuiping Jiang³  Jiao Sun³  Changyu Pan⁴  Jihu Li⁵  Xiaolin Zhu⁵  Bin Zhao⁵ 

[1] Department of Cardiology, Peking University People’s Hospital, Beijing, China;Department of Endocrinology and Metabolism, Peking University People’s Hospital, Beijing, China;Department of Endocrinology, Huadong Hospital Affiliated to Fudan University, 221 yananxi road, 200040, Shanghai, China;Department of Endocrinology, The Chinese PLA General Hospital, Beijing, China;MSD China Holding Co., Ltd., Shanghai, China;

关键词: Socioeconomic status;    Type 2 diabetes;    Blood glucose;    Blood pressure;    Blood lipids;    Diabetes complications;   

DOI  :  10.1186/s12933-016-0376-7

 received in 2016-01-01, accepted in 2016-03-25,  发布年份 2016

来源: Springer

【 摘 要 】

BackgroundLow socioeconomic status (SES) is associated with adverse cardiovascular risk factor patterns and poor outcomes in patients with diabetes. The aim of this study was to determine whether SES is associated with the control of blood glucose, blood pressure, blood cholesterol (3Bs), and diabetic complications in Chinese adults with type 2 diabetes.MethodsData regarding patients’ demographics, social economics, diabetes complications, and cardiovascular risk profiles were analyzed for 25,454 patients. The outcomes of interest were the proportions of patients with HbA1c <7.0 %, blood pressure <140/80 mmHg, total serum cholesterol <4.5 mmol/L, and diabetes complications. Multivariable logistic regression was used for analysis.ResultsOf the 25,454 patients, the least educated patients (1695, 6.7 %) had the highest chances of developing cardiovascular diseases (p = 0.048), cerebrovascular diseases (p < 0.001), and retinopathy (p < 0.001). The patients with lowest household income (10,039, 40.8 %) had the highest prevalence of retinopathy (p < 0.001) and neuropathy (p < 0.001). The most educated patients were more likely than the least educated patients to achieve HbA1c <7.0 % [adjusted odds ratio (OR) 1.38; 95 % confidence interval (95 % CI) 1.22–1.56] and 3B goals (adjusted OR 1.30; 95 % CI 1.11–1.53). The patients with highest household income were more likely to achieve BP < 140/80 mmHg (adjusted OR 1.16; 95 % CI 1.07–1.27), but less likely to reach HbA1c < 7.0 % (adjusted OR 0.90; 95 % CI 0.83–0.98) than those lowest income patients.ConclusionsLow SES was associated with poor metabolic control and more diabetes complications in adult patients in China. Individual diabetes management based on the SES of patients is encouraged.

【 授权许可】

CC BY   
© Tao et al. 2016