Vapoenucleation of the prostate using a high-power thulium laser: a one-year follow-up study

BMC Urology

Research Article

Yen-Hwa Chang¹  William JS Huang¹  Kuang-Kuo Chen¹  Alex TL Lin¹  Tzu-Ping Lin¹  Ching-Hsin Chang² 

[1] Department of Urology, Taipei Veterans General Hospital, Taipei, Taiwan;Department of Urology, National Yang-Ming University School of Medicine, Taipei, Taiwan;Shu-Tien Urological Science Research Center, Taipei, Taiwan;Department of Urology, Taipei Veterans General Hospital, Taipei, Taiwan;Department of Urology, Taipei Medical University Hospital, Taipei, Taiwan;Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan;

关键词: Benign prostate enlargement;    Quanta thulium surgical laser system;    Thulium laser;    Vapoenucleation;   

DOI  :  10.1186/s12894-015-0032-7

 received in 2014-07-05, accepted in 2015-04-16,  发布年份 2015

来源: Springer

【 摘 要 】

BackgroundProstate vaporization and enucleation is a novel treatment option for bladder outlet obstruction caused by benign prostate enlargement. This surgical technique, however, has not yet been standardized. We present our findings of using a high-power thulium laser to accomplish vapoenucleation of the prostate (ThuVEP).MethodsWe prospectively collected and analyzed data from 29 patients who underwent ThuVEP between August 2010 and May 2012. The control group included 30 patients who underwent traditional transurethral resection of the prostate (TURP). Operative variables, patient profiles, preoperative and postoperative urine flow rates, prostate volume (measured using transrectal ultrasonography), and the international prostate symptom score (IPSS) were recorded and analyzed using a two-tailed Student’s t-test and analysis of variance.ResultsThe ages (mean ± SD) of the patients were 76.1 ± 9.4 and 72.6 ± 7.4 years (p = 0.28) in the ThuVEP and TURP groups, respectively. The average urinary flow rates before and 12 months after the operation (volume/maximum flow/average flow) were 243.3/10.5/5.0 and 302.8/17.6/9.4 (in mL, mL/s, mL/s, respectively) in the ThuVEP group and 247.2/10.8/4.6 and 369.9/20.8/12.0, respectively, in the TURP group. Preoperative and postoperative IPSSs were 17.1 ± 5.0 and 6.5 ± 3.8, respectively, in the ThuVEP group and 18.2 ± 4.5 and 6.2 ± 3.3, respectively, in the TURP group. The mean ratio of the estimated postoperative residual prostate volume to the preoperative total volume was 0.47 (p = 0.449) in both groups. The overall complication rate was 20.7% in the ThuVEP group and 30.0% in the TURP group.ConclusionsOne year of follow-up showed that ThuVEP and TURP effectively alleviated subjective and objective voiding symptoms with a low rate of complications. Thus, vapoenucleation using a high-power laser is feasible in elderly patients.Trial registrationISRCTN registry with study ID ISRCTN52339705. Date assigned: 06/03/2015.

【 授权许可】

Unknown   
© Chang et al.; licensee BioMed Central. 2015. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.