Assessment of Sexual Outcomes in Patients Undergoing Thulium Laser Prostate Surgery for Management of Benign Prostate Hyperplasia: A Systematic Review and Meta-analysis

Sexual Medicine

Jianjun Zhang, MD¹  Longjun Cai, MD¹  Chendi Yang, MD²  Bibo Li, PhD, MD³  Conghui Han, PhD, MD⁴  Xitao Wang, MD⁴  Kun Pang, PhD, MD⁴  Guanghui Zang, PhD, MD⁴  Lin Hao, MD⁴  Jian Wang, MD⁴ 

[1] Suqian People's Hospital of Nanjing Drum-Tower Hospital Group, the Affiliated Suqian Hospital of Xuzhou Medical University, Suqian, China;Suzhou Hospital of Chinese Medicine, Suzhou, China;Taizhou Hospital Affiliated to Nanjing University of Chinese Medicine, Taizhou, China;Xuzhou Central Hospital, Xuzhou, China;

关键词: Thulium laser;    Prostate surgery;    Prostate hyperplasia;    Sexual outcomes;    Erectile function;   

DOI  :  

来源: DOAJ

【 摘 要 】

ABSTRACT:Background: Thulium laser (Tm:YAG) prostate surgery is a safe and effective procedure with low morbidity and comparable clinical outcomes to those of transurethral resection of the prostate (TURP). However, the sexual function outcomes (erectile and ejaculatory function) have been scarcely studied. Aim: We aimed to assess the impact of Tm:YAG prostate surgery on sexual outcomes (erectile and ejaculatory function) and compare them with those patients undergoing TURP. Material and Methods: We searched digital databases like PUBMED, SCOPUS, CENTRAL and EMBASE using relevant keywords to identify comparative studies on TURP and non-comparative studies on Tm:YAG prostate surgery that assessed sexual outcomes. We performed qualitative and quantitative analyses with the extracted data. We carried out a meta-analysis to compare postoperative International Index of Erectile Function (IIEF-5) scores and incidences of retrograde ejaculation (RE) in patients undergoing either Tm:YAG or TURP. The pre-operative and post-operative IIEF-5 scores were pooled to estimate overall scores. Results: We included 5 comparative and 8 non-comparative studies in this review. We found the postoperative IIEF-5 score improvements to be significantly higher in the Tm:YAG prostate surgery group than in the TURP group with a significant mean difference (MD) of 0.45 (95% CI, 0.18 to 0.72; P = .001). We found no significant associations between the procedures. The pooled OR for the association of RE was estimated at 0.90 (95% CI, 0.50 to 1.60; P = .71; I2 = 0%). Conclusion: Tm:YAG prostate surgery improves erectile function more than TURP, according to our findings. Tm:YAG prostate aided surgery also outperforms TURP in terms of preserving sexual function following surgery.However, We found similar or no difference in incidence of RE between Tm:YAG prostate surgery and TURP.Bibo L, Hao L, Pang K, et al. Assessment of Sexual Outcomes in Patients Undergoing Thulium Laser Prostate Surgery for Management of Benign Prostate Hyperplasia: A Systematic Review and Meta-analysis. Sex Med 2022;10:100483.

【 授权许可】

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