Genomic survey, expression profile and co-expression network analysis of OsWD40 family in rice

BMC Genomics

Research Article

Zhanhua Lu¹  Xiaolong Huang²  Jialing Yao²  Yidan Ouyang³ 

[1] College of Horticulture and Forestry Science, Huazhong Agricultural University, 430070, Wuhan, China;College of Life Science and Technology, Huazhong Agricultural University, 430070, Wuhan, China;National Key Laboratory of Crop Genetic Improvement and National Center of Plant Gene Research (Wuhan), Huazhong Agricultural University, 430070, Wuhan, China;

关键词: Oryza sativa;    Expression profiles;    Microarray;    WD40;    Co-expression network;   

DOI  :  10.1186/1471-2164-13-100

 received in 2011-08-16, accepted in 2012-03-20,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundWD40 proteins represent a large family in eukaryotes, which have been involved in a broad spectrum of crucial functions. Systematic characterization and co-expression analysis of OsWD40 genes enable us to understand the networks of the WD40 proteins and their biological processes and gene functions in rice.ResultsIn this study, we identify and analyze 200 potential OsWD40 genes in rice, describing their gene structures, genome localizations, and evolutionary relationship of each member. Expression profiles covering the whole life cycle in rice has revealed that transcripts of OsWD40 were accumulated differentially during vegetative and reproductive development and preferentially up or down-regulated in different tissues. Under phytohormone treatments, 25 OsWD40 genes were differentially expressed with treatments of one or more of the phytohormone NAA, KT, or GA3 in rice seedlings. We also used a combined analysis of expression correlation and Gene Ontology annotation to infer the biological role of the OsWD40 genes in rice. The results suggested that OsWD40 genes may perform their diverse functions by complex network, thus were predictive for understanding their biological pathways. The analysis also revealed that OsWD40 genes might interact with each other to take part in metabolic pathways, suggesting a more complex feedback network.ConclusionsAll of these analyses suggest that the functions of OsWD40 genes are diversified, which provide useful references for selecting candidate genes for further functional studies.

【 授权许可】

Unknown   
© Ouyang et al; licensee BioMed Central Ltd. 2012. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.