Behavior in a stressful situation, personality factors, and disease severity in patients with acute myocardial infarction: baseline findings from the prospective cohort study SECAMI (The Secondary Prevention and Compliance following Acute Myocardial Infarction-study)

BMC Cardiovascular Disorders

Research Article

Mona Schlyter¹  Patrik Tydén¹  Bo Hedblad²  Gunnar Engström²  Lena André-Petersson³ 

[1] Department of Cardiology, Lund University, Skåne University Hospital, Malmö, Sweden;Department of Clinical Sciences, Lund University, Skåne University Hospital, Malmö, Sweden;Department of Clinical Sciences, Lund University, Skåne University Hospital, Malmö, Sweden;Department of Neurology, Skåne University Hospital, Malmö, Sweden;

关键词: Myocardial Infarction;    Left Ventricular Ejection Fraction;    Acute Myocardial Infarction;    Personality Dimension;    Maladaptive Behavior;   

DOI  :  10.1186/1471-2261-11-45

 received in 2010-12-28, accepted in 2011-07-21,  发布年份 2011

来源: Springer

【 摘 要 】

BackgroundPsychosocial stress has been identified as a risk factor in association with cardiovascular disease but less attention has been paid to heterogeneity in vulnerability to stress. The serial Color Word Test (CWT) measures adaptation to a stressful situation and it can be used to identify individuals that are vulnerable to stress. Prospective studies have shown that individuals with a maladaptive behavior in this test are exposed to an increased risk of future cardiovascular events. The aim of the present study was to investigate whether maladaptive behavior in the serial CWT alone or in combination with any specific personality dimension was associated with severity of myocardial infarction (MI).MethodsMI-patients (n = 147) completed the test and filled in a personality questionnaire in close proximity to the acute event. The results were analyzed in association with four indicators of severity: maximum levels above median of the cardiac biomarkers troponin I and creatine kinase-MB (CKMB), Q-wave infarctions, and a left ventricular ejection fraction (LVEF) ≤ 50%.ResultsMaladaptive behavior in the serial CWT together with low scores on extraversion were associated with maximum levels above median of cardiac troponin I (OR 2.97, CI 1.08-8.20, p = 0.04) and CKMB (OR 3.33, CI 1.12-9.93, p = 0.03). No associations were found between the combination maladaptive behavior and low scores on extraversion and Q-wave infarctions or a decreased LVEF.ConclusionsMaladaptive behavior in combination with low scores on extraversion is associated with higher cardiac biomarker levels following an MI. The serial CWT and personality questionnaires could be used to identify individuals vulnerable to the hazardous effects of stress and thereby are exposed to an increased risk of a more severe infarction.

【 授权许可】

CC BY   
© André-Petersson et al; licensee BioMed Central Ltd. 2011