Prevalence and correlates of depressive symptoms in HIV-positive patients: a cross-sectional study among newly diagnosed patients in Yaoundé, Cameroon

BMC Psychiatry

Research Article

Yixin Fang¹  Félicien Enyime Ntone²  Christopher Kuaban³  Jean Jacques N Noubiap⁴  Rodrigue Minya L’akoa⁵ 

[1] Department of Population Health, Division of Biostatistics, New York School of Medicine, New York, NY, USA;Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon;Department of Psychiatry, Yaoundé Jamot Hospital, Yaoundé, Cameroon;Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon;Department of Psychiatry, Yaoundé Jamot Hospital, Yaoundé, Cameroon;Faculty of Health Sciences, University of Bamenda, Bamenda, Cameroon;Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon;Internal Medicine Unit, Edéa Regional Hospital, Edéa, Cameroon;Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon;Nguelemendouka District Hospital, Nguelemendouka, Cameroon;

关键词: Depressive symptoms;    HIV patients;    Cameroon;   

DOI  :  10.1186/1471-244X-13-228

 received in 2013-02-18, accepted in 2013-09-18,  发布年份 2013

来源: Springer

【 摘 要 】

BackgroundDepression is one of the most common neuropsychiatric complications of HIV disease, and in turn it is associated with worse HIV-related outcomes. Data on depression among HIV-infected patients in Cameroon are scarce. In this study, we report the prevalence and correlates of depressive symptoms among newly diagnosed HIV-infected patients in Yaoundé, Cameroon.MethodsInterviews were conducted with 100 newly diagnosed HIV-infected patients at three referral hospitals of Yaoundé. Depression was assessed using the nine-item Patient Health Questionnaire (PHQ-9). A positive depression screen was defined as PHQ-9 score greater than 9.ResultsThe overall prevalence of depressive symptoms was 63% (95% CI: 53.2 to 71.8), the majority having symptoms corresponding to moderate depression. Multiple logistic regression analysis showed that probable depressed patients were more likely than those who were not depressed to have had experience of alcohol abuse (OR: 19.03, 95% CI 3.11-375.85; p = 0.0083), and a 100 CD4 cells/mm3 fewer was associated with a 2.9 times increase of the odds of probable depression (95% CI 1.88-4.84; p < 0.0001).ConclusionsOur findings indicate a high prevalence of depressive symptoms in newly diagnosed HIV-infected patients in our setting, and their association with alcohol abuse and severe immunosuppression. This study also highlights the necessity to integrate mental health interventions into routine HIV clinical care in Cameroon.

【 授权许可】

Unknown   
© L’akoa et al.; licensee BioMed Central Ltd. 2013. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.