Prevalence and correlates of depressive symptoms in HIV-positive patients: a cross-sectional study among newly diagnosed patients in Yaoundé, Cameroon

BMC Psychiatry

Christopher Kuaban³  Félicien Enyime Ntone⁵  Yixin Fang¹  Jean Jacques N Noubiap²  Rodrigue Minya L’akoa⁴ 

[1] Department of Population Health, Division of Biostatistics, New York School of Medicine, New York, NY, USA;Internal Medicine Unit, Edéa Regional Hospital, Edéa, Cameroon;Faculty of Health Sciences, University of Bamenda, Bamenda, Cameroon;Nguelemendouka District Hospital, Nguelemendouka, Cameroon;Department of Psychiatry, Yaoundé Jamot Hospital, Yaoundé, Cameroon

关键词: Cameroon;    HIV patients;    Depressive symptoms;   

Others  :  1123965
DOI  :  10.1186/1471-244X-13-228

 received in 2013-02-18, accepted in 2013-09-18,  发布年份 2013

【 摘 要 】

Background

Depression is one of the most common neuropsychiatric complications of HIV disease, and in turn it is associated with worse HIV-related outcomes. Data on depression among HIV-infected patients in Cameroon are scarce. In this study, we report the prevalence and correlates of depressive symptoms among newly diagnosed HIV-infected patients in Yaoundé, Cameroon.

Methods

Interviews were conducted with 100 newly diagnosed HIV-infected patients at three referral hospitals of Yaoundé. Depression was assessed using the nine-item Patient Health Questionnaire (PHQ-9). A positive depression screen was defined as PHQ-9 score greater than 9.

Results

The overall prevalence of depressive symptoms was 63% (95% CI: 53.2 to 71.8), the majority having symptoms corresponding to moderate depression. Multiple logistic regression analysis showed that probable depressed patients were more likely than those who were not depressed to have had experience of alcohol abuse (OR: 19.03, 95% CI 3.11-375.85; p = 0.0083), and a 100 CD4 cells/mm3 fewer was associated with a 2.9 times increase of the odds of probable depression (95% CI 1.88-4.84; p < 0.0001).

Conclusions

Our findings indicate a high prevalence of depressive symptoms in newly diagnosed HIV-infected patients in our setting, and their association with alcohol abuse and severe immunosuppression. This study also highlights the necessity to integrate mental health interventions into routine HIV clinical care in Cameroon.

【 授权许可】

   
2013 L’akoa et al.; licensee BioMed Central Ltd.

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