Rapid emotional processing in relation to trauma-related symptoms as revealed by magnetic source imaging

BMC Psychiatry

Research Article

James Moran¹  Maggie Schauer¹  Inga Schalinski¹  Thomas Elbert¹ 

[1] Department of Psychology, University of Konstanz, P.O. Box 905, 78457, Konstanz, Germany;

关键词: PTSD;    MEG;    IAPS;    Shutdown;    Dissociation;    Depression;   

DOI  :  10.1186/1471-244X-14-193

 received in 2014-01-30, accepted in 2014-07-03,  发布年份 2014

来源: Springer

【 摘 要 】

BackgroundTraumatic stress leads to functional reorganization in the brain and may trigger an alarm response. However, when the traumatic event produces severe helplessness, the predominant peri-traumatic response may instead be marked by a dissociative shutdown reaction. The neural correlates of this dissociative shutdown were investigated by presenting rapidly presented affective pictures to female participants with posttraumatic stress disorder (PTSD), and comparing responses to a Non-PTSD control group.MethodsEvent-related-magnetic-fields were recorded during rapid visual serial presentation of emotionally arousing stimuli (unpleasant or pleasant), which alternated with pictures with low affective content (neutral). Neural sources, based on the L2-surface-minimum-norm, correlated with the severity of the symptom clusters: PTSD, depression and shutdown dissociation.ResultsFor the early cortical response (60 to 110 ms), dissociation and PTSD symptom severity show similar spatial distributions of correlates for unpleasant stimuli. Cortical networks that could be involved in the relationships seem to be widespread.ConclusionWe conclude that shutdown dissociation, PTSD and depression all have distinct effects on early processing of emotional stimuli.

【 授权许可】

CC BY   
© Schalinski et al.; licensee BioMed Central Ltd. 2014