Choroidal thickness measurement by enhanced depth imaging and swept-source optical coherence tomography in central serous chorioretinopathy

BMC Ophthalmology

Research Article

Ferdiriva Hamzah¹  Ari Shinojima²  Mitsuko Yuzawa²  Ryusaburo Mori² 

[1] Department of Ophthalmology, School of Medicine, Surugadai Hospital of Nihon University, 1-8-13 Surugadai, 101-8309, Kanda, Chiyodaku, Tokyo, Japan;Jakarta Eye Center, Jakarta, Indonesia;Jakarta Eye Center, Jakarta, Indonesia;

关键词: Optical Coherence Tomography;    Retinal Pigment Epithelium;    Macular Hole;    Choroidal Thickness;    Central Serous Chorioretinopathy;   

DOI  :  10.1186/1471-2415-14-145

 received in 2014-05-13, accepted in 2014-11-19,  发布年份 2014

来源: Springer

【 摘 要 】

BackgroundWe evaluated subfoveal choroidal thickness measured with two different forms of optical coherence tomography (OCT), enhanced-depth imaging (EDI) and swept-source (SS) OCT, in central serous chorioretinopathy (CSC).MethodsFifty-six eyes of 48 patients diagnosed with acute or chronic CSC, were studied prospectively. Subfoveal choroidal thickness was measured as the distance between the outer border of the retinal pigment epithelium-Bruch’s membrane complex, and the chorioscleral border under the fovea. Subfoveal choroidal thickness was measured using EDI-OCT and SS-OCT. We also measured serous retinal detachment (SRD) only with SS-OCT. The Pearson correlation coefficient was used to assess the correlation between subfoveal choroidal thickness values determined by the two different OCT modalities.ResultsThe mean patient age was 52 ± 13 years (range, 32–82 years). Among the 56 eyes, 21 had acute CSC and 35 had chronic CSC. Subfoveal choroidal thickness measured with EDI-OCT was 336.6 ± 91.6 μm in acute and 388.0 ± 103.4 μm in chronic CSC. With SS-OCT, the thickness in acute CSC was 332.0 ± 96.7 μm and that in chronic CSC was 392.6 ± 101.3 μm. Acute CSC (p <0.001, correlation coefficient; r = 0.99) and chronic CSC (p <0.001, correlation coefficient; r = 0.97) values obtained with the two different OCT modalities correlated significantly. Among the 56 eyes, 43 (19 eyes with acute and 24 with chronic CSC) were evaluable for SRD height by SS-OCT. The mean SRD height was 128.9 ± 83.6 μm in acute cases and 96.3 ± 62.0 μm in chronic cases.ConclusionsSubfoveal choroidal thickness obtained with two different OCT modalities correlated significantly.

【 授权许可】

Unknown   
© Hamzah et al.; licensee BioMed Central Ltd. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.