Changes in obesity-related diseases and biochemical variables after laparoscopic sleeve gastrectomy: a two-year follow-up study

BMC Surgery

Research Article

Vetle Aaberge Sande¹  Gunnar Mellgren²  Villy Våge³  Camilla Laukeland³  Jan Behme³  John Roger Andersen⁴ 

[1] Department of Clinical Science, University of Bergen, 5020, Bergen, Norway;Department of Clinical Science, University of Bergen, 5020, Bergen, Norway;Hormone Laboratory, Haukeland University Hospital, 5021, Bergen, Norway;Department of Surgery, Førde Central Hospital, 6807, Førde, Norway;Department of Surgery, Førde Central Hospital, 6807, Førde, Norway;Department of Health, Sogn og Fjordane University College, 6803, Førde, Norway;

关键词: Sleeve gastrectomy;    Obesity;    Comorbidities;    Complications;   

DOI  :  10.1186/1471-2482-14-8

 received in 2013-07-08, accepted in 2014-02-05,  发布年份 2014

来源: Springer

【 摘 要 】

BackgroundTo evaluate changes in obesity-related diseases and micronutrients after laparoscopic sleeve gastrectomy (LSG).MethodsWe started the procedure in May 2007, and by December 2011, 117 patients could be evaluated for a two year follow-up. Comparisons of preoperative status with 12 and 24 months postoperative status were made for body mass index (BMI), obesity-related diseases and micronutrients.ResultsMajor complications included bleeding requiring transfusion at 5.1%, leak at 1.7% and abscess without a visible leak at 0.9%. Mean BMI was reduced from 46.6 (standard deviation (SD) 6.0) kg/m2 to 30.6 (SD 5.6) kg/m2 at two years, and resolution occurred for 80.7% of patients with type 2 diabetes, 63.9% with hypertension, 75.8% with hyperlipidemia, 93.0% with sleep apnea, 31.4% with musculoskeletal pain, 85.4% with snoring and 73.3% with urinary incontinence. Amenorrhea resolved in all premenopausal females. The proportion of patients with symptomatic gastroesophageal reflux disease increased from 12.8% to 27.4%. The prevalence of patients with low ferritin-levels increased, while 25-hydroxyvitamin D (25(OH)D) deficiency decreased postoperatively.ConclusionsLSG is an effective procedure for morbid obesity and obesity-related diseases, but the technique should be further explored particularly to avoid gastroesophageal reflux.

【 授权许可】

CC BY   
© Våge et al.; licensee BioMed Central Ltd. 2014