Degree of agreement among sepsis diagnosis criteria in adult emergency room patients with infection

1st International Conference on Tropical Medicine and Infectious Diseases (ICTROMI) Faculty of Medicine Universitas Sumatera Utara

Sinto, R.^1 ; Chandra, A.T.^2 ; Lie, K.C.^1 ; Suwarto, S.^1

Division of Tropical and Infectious Diseases, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, CiptoMangunkusumo National Hospital, Jalan Diponegoro No 71, Jakarta, Indonesia^1

Faculty of Medicine Universitas Atmajaya, Jalan Pluit Raya 2, Jakarta, Indonesia^2

关键词: Agreement coefficient;    Comorbidities;    Cross-sectional study;    Diagnosis criteria;    Indonesia;    Indonesians;    Infected patients;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/125/1/012022/pdf
DOI  :  10.1088/1755-1315/125/1/012022

来源: IOP

【 摘 要 】

The study on the degree of agreement among three established sepsis diagnosis criteria become the necessity to investigate the best sepsis diagnosis criteria in Indonesia further. A cross-sectional study of adult Emergency Room patients hospitalized with a diagnosis of infection in CiptoMangunkusumo Hospital, Indonesia was conducted during March and April 2017. We recorded diagnosis, gender, age, comorbidities, infection source, and origin. Every subject was classified into sepsis and non-sepsis based on 1991, 2001 and sepsis-3 criteria. Raw % and Kappa agreement coefficients (κ) were calculated according to previously established formula to measure the degree of agreement among three diagnostic criteria. As many as 278 subjects were included in this study. The raw % agreement and κ between 1991 and 2001 criteria is 69.07% and 0.34 respectively. The raw % agreement and κ between 2001 and sepsis-3 criteria is 56.12% and 0.15 respectively. The raw % agreement and κ between 1991 and sepsis-3 criteria is 48.19% and -0.02. In conclusions, there is afair agreement between 1991 and 2001 criteria, poor agreement between 2001 and sepsis-3 criteria, and poor disagreement between 1991 and sepsis-3 criteria. This necessitates further Indonesian study of the best diagnosis criteria to diagnose an infected patient with sepsis.