Impaired pitch identification as a potential marker for depression

BMC Psychiatry

Research Article

Klaus Mathiak¹  Michael Schwenzer¹  Eva Zattarin¹  Michael Grözinger¹ 

[1] Department of Psychiatry, Psychotherapy and Psychosomatic Medicine, RWTH Aachen University, Pauwelsstr. 30, D-52074, Aachen, Germany;

关键词: Depression;    Non-verbal processing;    Pitch identification;    Motivation;    Sex effect;   

DOI  :  10.1186/1471-244X-12-32

 received in 2011-09-01, accepted in 2012-02-24,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundImpaired auditory performance has been considered as marker for depression. The present study tested whether pitch perception is affected in depression and whether the impairment is task-specific or reflects global dysfunction.MethodsTwelve depressive in-patients and 12 non-depressive participants, half of the sample women, volunteered. The participants performed pitch identification using a four-choice reaction task, pitch contour perception, and pitch discrimination.ResultsDuring pitch identification but not during pitch contour perception or pitch discrimination, depressive patients responded less accurate than non-depressive participants (F = 3.3, p = 0.047). An analysis of covariates revealed that only female but not male depressive patients identified pitches poorly (Z = −2.2, p = 0.025) and inaccurate pitch identification correlated with high scores in the Beck Depression Inventory in women (r = −0.8, p = 0.001) but not in men (r = −0.1, p = 0.745). Patients did not differ from controls in reaction time or responsiveness.ConclusionsImpaired pitch perception in depression is task-specific. Therefore, cognitive deficits in depression are circumscribed and not global. Reduced pitch identification in depression was associated with female sex. We suggest that impaired pitch identification merits attention as a potential marker for depression in women.

【 授权许可】

CC BY   
© Schwenzer et al.; licensee BioMed Central Ltd. 2012