The CROWN initiative: journal editors invite researchers to develop core outcomes in women’s health

BMC Pregnancy and Childbirth

Editorial

Khalid Khan¹  Peter O’Donovan² 

[1] BJOG: An International Journal of Obstetrics and Gynaecology, London, UK;Chief Editors of Journals participating in The CROWN Initiative listed at the end of this article, UK;BMC Series, 236 Gray’s Inn Road, WC1X 8HB, London, UK;

关键词: Research design/standards;    Treatment outcome;    Endpoint determination/standards;    Clinical trials;    Systematic reviews;    Guidelines;    Bias (Epidemiology);    Evidence-based medicine;    Consensus;   

DOI  :  10.1186/1471-2393-14-199

 received in 2014-05-29, accepted in 2014-06-10,  发布年份 2014

来源: Springer

【 摘 要 】

Clinical trials, systematic reviews and guidelines compare beneficial and non-beneficial outcomes following interventions. Often, however, various studies on a particular topic do not address the same outcomes, making it difficult to draw clinically useful conclusions when a group of studies is looked at as a whole. This problem was recently thrown into sharp focus by a systematic review of interventions for preterm birth prevention, which found that among 103 randomised trials, no fewer than 72 different outcomes were reported. There is a growing recognition among clinical researchers that this variability undermines consistent synthesis of the evidence, and that what is needed is an agreed standardised collection of outcomes - a “core outcomes set” - for all trials in a specific clinical area. Recognising that the current inconsistency is a serious hindrance to progress in our specialty, the editors of over 50 journals related to women’s health have come together to support The CROWN (CoRe Outcomes in WomeN’s health) Initiative.

【 授权许可】

Unknown   
© Khan and O'Donovan; licensee BioMed Central Ltd. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.