Depression after low-energy fracture in older women predicts future falls: a prospective observational study

BMC Geriatrics

Research Article

Noortje A Verdijk¹  Colette JM Wijnands-van Gent²  Arnold C Romeijnders²  Geraline L Leusink³  Victor JM Pop⁴  Martha van den Berg⁴  Joop PW van den Bergh⁵ 

[1] Diagnostiek voor U, PO Box 2406, 5600, Eindhoven, CK, The Netherlands;PoZoB, Coordination Centre of Practice Nurses for South East Netherlands, PO Box 312, 5500, Veldhoven, AH, The Netherlands;Stichting Severinus, PO Box 6666, 5500, Veldhoven, MA, The Netherlands;Tilburg University, CoRPS - Center of Research on Psychology in Somatic diseases, PO Box 90153, 5000, Tilburg, LE, The Netherlands;VieCuri Medical Centre Noord-Limburg, Department of Internal Medicine, PO Box 1926, 5900, Venlo, BX, The Netherlands;Maastricht University/Nutrim, Faculty of Health Medicine and Life Science, Department of Internal Medicine, PO Box 616, 6200, Maastricht, MD, The Netherlands;

关键词: Bone Mineral Density;    Edinburgh Postnatal Depression Scale;    Femoral Neck Bone Mineral Density;    Bone Mineral Density Test;    Recent Fracture;   

DOI  :  10.1186/1471-2318-11-73

 received in 2011-05-31, accepted in 2011-11-07,  发布年份 2011

来源: Springer

【 摘 要 】

BackgroundFalls are one of the main causes of fractures in elderly people and after a recent fracture, the risk of another fall is increased, resulting in subsequent fracture. Therefore, risk factors for future falls should be determined. We prospectively investigated the relationship between depression and the incidence of falls in post-menopausal women after a low-energy fracture.MethodsAt baseline, 181 women aged 60 years and older who presented with a recent low-energy fracture were evaluated at the fracture and osteoporosis outpatient clinics of two hospitals. As well as clinical evaluation and bone mineral density tests, the presence of depression (measured using the Edinburgh Depression Scale, EDS, depression cut-off > 11) and risk factors for falling were assessed. During two years of follow-up, the incidence of falls was registered annually by means of detailed questionnaires and interviews.ResultsSeventy-nine (44%) of the women sustained at least one fall during follow-up. Of these, 28% (n = 22) suffered from depression at baseline compared to 10% (n = 10) of the 102 women who did not sustain a fall during follow-up (Χ2 = 8.76, df = 1, p = .003). Multiple logistic regression showed that the presence of depression and co-morbidity at baseline were independently related to falls (OR = 4.13, 95% CI = 1.58-10.80; OR = 2.25, 95% CI = 1.11-4.56, respectively) during follow-up.ConclusionsThe presence of depression in women aged 60 years and older with recent low-energy fractures is an important risk factor for future falls. We propose that clinicians treating patients with recent low-energy fractures should anticipate not only on skeletal-related risk factors for fractures, but also on fall-related risk factors including depression.

【 授权许可】

CC BY   
© van den Berg et al; licensee BioMed Central Ltd. 2011