Clinical and sociodemographic correlates of suicidality in patients with major depressive disorder from six Asian countries

BMC Psychiatry

Research Article

Jin Pyo Hong¹  Ah-Rong Lee¹  Ah-Young Lim¹  Chia-Yih Liu²  Hong Jin Jeon³  Pichet Udomratn⁴  Shen-Ing Liu⁵  Ahmad Hatim⁶  Hong Choon Chua⁷  Si Tian-Mei⁸  Edwin Chan⁹  Dianne Bautista⁹ 

[1] Department of Psychiatry, Asan Medical Center, Ulsan University College of Medicine, Seoul, South Korea;Department of Psychiatry, Chang Gung Medical Center and Chang Gung University, Tao-Yuan County, Taiwan;Department of Psychiatry, Depression Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea;Department of Psychiatry, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand;Department of Psychiatry, Mackay Memorial Hospital, New Taipei City, Taiwan;Department of Psychological Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia;Institute of Mental Health, Woodbridge Hospital, Singapore, Singapore;Peking University Institute of Mental Health, Beijing, China;Singapore Clinical Research Institute, Singapore, Singapore;Duke-National University of Singapore, Singapore, Singapore;

关键词: Suicide;    Major depressive disorder;    Risk factor;    Social support;   

DOI  :  10.1186/1471-244X-14-37

 received in 2013-12-16, accepted in 2014-02-05,  发布年份 2014

来源: Springer

【 摘 要 】

BackgroundEast Asian countries have high suicide rates. However, little is known about clinical and sociodemographic factors associated with suicidality in Asian populations. The aim of this study was to evaluate the factors associated with suicidality in patients with major depressive disorder (MDD) from six Asian countries.MethodsThe study cohort consisted of 547 outpatients with MDD. Patients presented to study sites in China (n = 114), South Korea (n = 101), Malaysia (n = 90), Singapore (n = 40), Thailand (n = 103), and Taiwan (n = 99). All patients completed the Mini-International Neuropsychiatric Interview (MINI), the Montgomery–Asberg Depression Rating Scale (MADRS), the Global Severity Index(SCL-90R), the Fatigue Severity Scale, the 36-item short-form health survey, the Sheehan Disability Scale, and the Multidimensional Scale of Perceived Social Support (MSPSS). Patients were classified as showing high suicidality if they scored ≥6 on the MINI suicidality module. Multivariate logistic regression analysis was used to examine sociodemographic and clinical factors related to high suicidality.ResultsOne hundred and twenty-five patients were classed as high suicidality. Unemployed status (adjusted odds ratio [OR] 2.43, p < 0.01), MADRS score (adjusted OR 1.08), p < 0.001, and GSI (SCL-90R) score (adjusted OR 1.06, p < 0.01) were positively related to high suicidality. Hindu (adjusted OR 0.09, p < 0.05) or Muslim (adjusted OR 0.21, p < 0.001) religion and MSPSS score (adjusted OR 0.82, p < 0.05) were protective against high suicidality.ConclusionsA variety of sociodemographic and clinical factors were associated with high suicidality in Asian patients with MDD. These factors may facilitate the identification of MDD patients at risk of suicide.

【 授权许可】

Unknown   
© Lim et al.; licensee BioMed Central Ltd. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.