Clinical and sociodemographic correlates of suicidality in patients with major depressive disorder from six Asian countries

BMC Psychiatry

Jin Pyo Hong²  Hong Choon Chua⁵  Shen-Ing Liu⁴  Edwin Chan¹  Dianne Bautista¹  Pichet Udomratn⁸  Hong Jin Jeon⁶  Chia-Yih Liu⁹  Si Tian-Mei⁷  Ahmad Hatim³  Ah-Rong Lee²  Ah-Young Lim² 

[1] Duke-National University of Singapore, Singapore, Singapore;Department of Psychiatry, Asan Medical Center, Ulsan University College of Medicine, Seoul, South Korea;Department of Psychological Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia;Department of Psychiatry, Mackay Memorial Hospital, New Taipei City, Taiwan;Institute of Mental Health, Woodbridge Hospital, Singapore, Singapore;Department of Psychiatry, Depression Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea;Peking University Institute of Mental Health, Beijing, China;Department of Psychiatry, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand;Department of Psychiatry, Chang Gung Medical Center and Chang Gung University, Tao-Yuan County, Taiwan

关键词: Social support;    Risk factor;    Major depressive disorder;    Suicide;   

Others  :  1123785
DOI  :  10.1186/1471-244X-14-37

 received in 2013-12-16, accepted in 2014-02-05,  发布年份 2014

【 摘 要 】

Background

East Asian countries have high suicide rates. However, little is known about clinical and sociodemographic factors associated with suicidality in Asian populations. The aim of this study was to evaluate the factors associated with suicidality in patients with major depressive disorder (MDD) from six Asian countries.

Methods

The study cohort consisted of 547 outpatients with MDD. Patients presented to study sites in China (n = 114), South Korea (n = 101), Malaysia (n = 90), Singapore (n = 40), Thailand (n = 103), and Taiwan (n = 99). All patients completed the Mini-International Neuropsychiatric Interview (MINI), the Montgomery–Asberg Depression Rating Scale (MADRS), the Global Severity Index(SCL-90R), the Fatigue Severity Scale, the 36-item short-form health survey, the Sheehan Disability Scale, and the Multidimensional Scale of Perceived Social Support (MSPSS). Patients were classified as showing high suicidality if they scored ≥6 on the MINI suicidality module. Multivariate logistic regression analysis was used to examine sociodemographic and clinical factors related to high suicidality.

Results

One hundred and twenty-five patients were classed as high suicidality. Unemployed status (adjusted odds ratio [OR] 2.43, p < 0.01), MADRS score (adjusted OR 1.08), p < 0.001, and GSI (SCL-90R) score (adjusted OR 1.06, p < 0.01) were positively related to high suicidality. Hindu (adjusted OR 0.09, p < 0.05) or Muslim (adjusted OR 0.21, p < 0.001) religion and MSPSS score (adjusted OR 0.82, p < 0.05) were protective against high suicidality.

Conclusions

A variety of sociodemographic and clinical factors were associated with high suicidality in Asian patients with MDD. These factors may facilitate the identification of MDD patients at risk of suicide.

【 授权许可】

   
2014 Lim et al.; licensee BioMed Central Ltd.

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