Back-to-Back Comparison of Auto-Fluorescence Imaging (AFI) Versus High Resolution White Light Colonoscopy for Adenoma Detection

BMC Gastroenterology

Technical Advance

Yusuke Saitoh¹  Yuhei Inaba²  Yoshiki Nomura²  Yutaka Kohgo²  Kentaro Moriichi²  Toshie Nata²  Hiroki Tanabe²  Takahiro Ito²  Kotaro Okamoto²  Kentaro Itabashi²  Nobuhiro Ueno²  Mikihiro Fujiya²  Chisato Ishikawa²  Yusuke Mizukami²  Shin Kashima³  Ryu Sato⁴  Shigeaki Maeda⁵  Jiro Watari⁶ 

[1] Digestive Disease Center, Asahikawa City Hospital, 1-1-65 Kinsei-cho, 070-8610, Asahikawa, Hokkaido, Japan;Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical University, 2-1 Midorigaoka-higashi, 078-8510, Asahikawa, Hokkaido, Japan;Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical University, 2-1 Midorigaoka-higashi, 078-8510, Asahikawa, Hokkaido, Japan;Internal Medicine, Kushiro Medical Association Hospital, 4-30 Nusamai-cho, Kushiro, 085-0836, Hokkaido, Japan;Internal Medicine, Kotoni Royal Hospital, 2-Nishi1-1-1, Hachiken, 063-0842, Nishi-ku, Sapporo, Hokkaido, Japan;Internal Medicine, Kushiro Medical Association Hospital, 4-30 Nusamai-cho, Kushiro, 085-0836, Hokkaido, Japan;Internal Medicine, Kushiro Medical Association Hospital, 4-30 Nusamai-cho, Kushiro, 085-0836, Hokkaido, Japan;Internal Medicine, Kushiro Medical Association Hospital, 4-30 Nusamai-cho, Kushiro, 085-0836, Hokkaido, Japan;Division of Upper Gastroenteroelogy, Department of Internal Medicine, Hyogo College of Medicine, 1-1 Mukogawa-cho, 663-8501, Nishinomiya, Hyogo, Japan;

关键词: Autofluorescence imaging;    Colorectal adenoma;    Detection rate;    Flat and depressed adenoma;    Less-experienced endoscopist;    High-resolution colonoscope;   

DOI  :  10.1186/1471-230X-12-75

 received in 2011-10-12, accepted in 2012-06-22,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundSome patients under close colonoscopic surveillance still develop colorectal cancer, thus suggesting the overlook of colorectal adenoma by endoscopists. AFI detects colorectal adenoma as a clear magenta, therefore the efficacy of AFI is expected to improve the detection ability of colorectal adenoma. The aim of this study is to determine the efficacy of AFI in detecting colorectal adenoma.MethodsThis study enrolled 88 patients who underwent colonoscopy at Asahikawa Medical University and Kushiro Medical Association Hospital. A randomly selected colonoscopist first observed the sigmoid colon and rectum with conventional high resolution endosopy (HRE). Then the colonoscopist changed the mode to AFI and handed to the scope to another colonoscopist who knew no information about the HRE. Then the second colonoscopist observed the sigmoid colon and rectum. Each colonoscopist separately recorded the findings. The detection rate, miss rate and procedural time were assessed in prospective manner.ResultsThe detection rate of flat and depressed adenoma, but not elevated adenoma, by AFI is significantly higher than that by HRE. In less-experienced endoscopists, AFI dramatically increased the detection rate (30.3%) and reduced miss rate (0%) of colorectal adenoma in comparison to those of HRE (7.7%, 50.0%), but not for experienced endoscopists. The procedural time of HRE was significantly shorter than that of AFI.ConclusionsAFI increased the detection rate and reduced the miss rate of flat and depressed adenomas. These advantages of AFI were limited to less-experienced endoscopists because experienced endoscopists exhibited a substantially high detection rate for colorectal adenoma with HRE.

【 授权许可】

Unknown   
© Moriichi et al.: licensee BioMed Central Ltd. 2012. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.