Back-to-Back Comparison of Auto-Fluorescence Imaging (AFI) Versus High Resolution White Light Colonoscopy for Adenoma Detection

BMC Gastroenterology

Yutaka Kohgo¹  Yusuke Saitoh³  Yusuke Mizukami¹  Hiroki Tanabe¹  Kotaro Okamoto¹  Takahiro Ito¹  Yuhei Inaba¹  Chisato Ishikawa¹  Kentaro Itabashi¹  Shin Kashima²  Shigeaki Maeda²  Nobuhiro Ueno¹  Toshie Nata¹  Yoshiki Nomura¹  Jiro Watari⁴  Ryu Sato²  Mikihiro Fujiya¹  Kentaro Moriichi¹ 

[1] Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical University, 2-1 Midorigaoka-higashi, Asahikawa, Hokkaido, 078-8510, Japan;Internal Medicine, Kushiro Medical Association Hospital, 4-30 Nusamai-cho, Kushiro, Hokkaido, 085-0836, Japan;Digestive Disease Center, Asahikawa City Hospital, 1-1-65 Kinsei-cho, Asahikawa, Hokkaido, 070-8610, Japan;Division of Upper Gastroenteroelogy, Department of Internal Medicine, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan

关键词: High-resolution colonoscope;    Less-experienced endoscopist;    Flat and depressed adenoma;    Detection rate;    Colorectal adenoma;    Autofluorescence imaging;   

Others  :  1113032
DOI  :  10.1186/1471-230X-12-75

 received in 2011-10-12, accepted in 2012-06-22,  发布年份 2012

【 摘 要 】

Background

Some patients under close colonoscopic surveillance still develop colorectal cancer, thus suggesting the overlook of colorectal adenoma by endoscopists. AFI detects colorectal adenoma as a clear magenta, therefore the efficacy of AFI is expected to improve the detection ability of colorectal adenoma. The aim of this study is to determine the efficacy of AFI in detecting colorectal adenoma.

Methods

This study enrolled 88 patients who underwent colonoscopy at Asahikawa Medical University and Kushiro Medical Association Hospital. A randomly selected colonoscopist first observed the sigmoid colon and rectum with conventional high resolution endosopy (HRE). Then the colonoscopist changed the mode to AFI and handed to the scope to another colonoscopist who knew no information about the HRE. Then the second colonoscopist observed the sigmoid colon and rectum. Each colonoscopist separately recorded the findings. The detection rate, miss rate and procedural time were assessed in prospective manner.

Results

The detection rate of flat and depressed adenoma, but not elevated adenoma, by AFI is significantly higher than that by HRE. In less-experienced endoscopists, AFI dramatically increased the detection rate (30.3%) and reduced miss rate (0%) of colorectal adenoma in comparison to those of HRE (7.7%, 50.0%), but not for experienced endoscopists. The procedural time of HRE was significantly shorter than that of AFI.

Conclusions

AFI increased the detection rate and reduced the miss rate of flat and depressed adenomas. These advantages of AFI were limited to less-experienced endoscopists because experienced endoscopists exhibited a substantially high detection rate for colorectal adenoma with HRE.

【 授权许可】

   
2012 Moriichi et al.: licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

Figure 3.

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