The association of sleep difficulties with health-related quality of life among patients with fibromyalgia

BMC Musculoskeletal Disorders

Research Article

Marco D DiBonaventura¹  Jan-Samuel Wagner¹  Arthi B Chandran²  Joseph C Cappelleri³ 

[1] Health Outcomes Practice, Kantar Health, 11 Madison Avenue, 12th Floor, 10010, New York, NY, USA;Pfizer Inc., 235-09-02, 235 East 42nd Street, 10017, New York, NY, USA;Pfizer Inc., 445 Eastern Point Road, MS 8260-2502, 06340, Groton, CT, USA;

关键词: Fibromyalgia;    Sleep;    Insomnia;    Health-related quality of life;    Pain;   

DOI  :  10.1186/1471-2474-13-199

 received in 2011-11-15, accepted in 2012-10-10,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundDifficulty sleeping is common among patients with fibromyalgia (FM); however, its impact on health-related quality of life (HRQoL) is not well understood. The aim of the current study was to assess the burden of sleep difficulty symptoms on HRQoL among patients with FM.MethodsThe current study included data from the 2009 National Health and Wellness Survey (N=75,000), which is a cross-sectional, Internet-based survey representative of the adult US population. The prevalence of sleep difficulty symptoms among patients with FM (n=2,196) were compared with matched controls (n=2,194), identified using propensity-score matching. Additionally, the relationship between the number of sleep difficulty symptoms (none, one, or two or more) and HRQoL (using the SF-12v2) was assessed using regression modeling, controlling for demographic and health history variables.ResultsOf the 2,196 patients with FM, 11.2% reported no sleep difficulty symptoms, 25.7% reported one sleep difficulty symptom, and 63.05% reported two or more sleep difficulty symptoms. The prevalence of sleep difficulty symptoms was significantly higher than matched controls. Patients with one and two sleep difficulty symptoms both reported significantly worse HRQoL summary and domain scores relative to those with no sleep difficulty symptoms (all p<.05). Further, the relationship between sleep difficulty symptoms and HRQoL was significantly different between those with FM than matched controls, suggesting a uniqueness of the burden of sleep difficulties within the FM population.ConclusionsAmong the FM population, sleep difficulty symptoms were independently associated with clinically-meaningful decrements in mental and physical HRQoL. These results suggest that greater emphasis in the treatment of sleep difficulty symptoms among the FM population may be warranted.

【 授权许可】

Unknown   
© Wagner et al.; licensee BioMed Central Ltd. 2012. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.