The severity of irritable bowel syndrome or the presence of fibromyalgia influencing the perception of visceral and somatic stimuli

BMC Gastroenterology

Research Article

Ennio Lubrano¹  Fabrizio Tremolaterra²  Yvonne Morra³  Serena Gallotta³  Carolina Ciacci³  Paola Iovino³ 

[1] Department of Medicine and Health Sciences, University of Molise, Via F. De Sanctis, 86100, Campobasso, Italy;Digestive Endoscopic Unit, Department of Surgery, A.O.R. "San Carlo", Via Potito Petrone, 85100, Potenza, Italy;Gastrointestinal Unit, Department of Medicine and Surgery, University of Salerno, Via S. Allende, 84081, Baronissi, SA, Italy;

关键词: Adult;    Female;    Irritable bowel syndrome/complications;    Irritable bowel syndrome/physiopathology;    Male;    Questionnaires;    Severity of illness index;    Fibromyalgia;    Functional bowel disorder severity index (FBDSI);   

DOI  :  10.1186/1471-230X-14-182

 received in 2013-06-15, accepted in 2014-10-09,  发布年份 2014

来源: Springer

【 摘 要 】

BackgroundFibromyalgia Syndrome (FMS) is a frequent comorbidity in Irritable Bowel Syndrome (IBS) patients with a higher functional bowel disorder severity index (FBDSI). We tested the possibility that mild to severe IBS patients without FMS would have a graduated visceral and somatic perception, and the presence of FMS would further enhance somatic, but conversely attenuate visceral perception.Our aim was to study visceral and somatic sensitivity in mild IBS patients and in severe IBS patients with or without FMS.MethodsEleven mild IBS and 19 severe IBS with and without FMS patients were studied. Somatic and visceral stimuli were applied in each patient by means of electrical stimulations at active and control sites and by means of an electronic barostat in the rectum. Thresholds for discomfort and perception cumulative scores were measured.ResultsMild and severe IBS patients without FMS demonstrated a significantly lower somatic perception cumulative score than severe IBS patients with FMS at active site. Conversely only severe IBS patients without FMS had significantly lower visceral thresholds for discomfort than mild IBS patients and severe IBS patients with FMS.ConclusionsThe presence of co-existing FMS or greater FBDSI affects somatic and visceral perception in a graded fashion across IBS patients.

【 授权许可】

Unknown   
© Tremolaterra et al.; licensee BioMed Central Ltd. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.