The severity of irritable bowel syndrome or the presence of fibromyalgia influencing the perception of visceral and somatic stimuli

BMC Gastroenterology

Paola Iovino³  Carolina Ciacci³  Ennio Lubrano²  Yvonne Morra³  Serena Gallotta³  Fabrizio Tremolaterra¹ 

[1] Digestive Endoscopic Unit, Department of Surgery, A.O.R. "San Carlo", Via Potito Petrone, 85100 Potenza, Italy;Department of Medicine and Health Sciences, University of Molise, Via F. De Sanctis, 86100 Campobasso, Italy;Gastrointestinal Unit, Department of Medicine and Surgery, University of Salerno, Via S. Allende, 84081 Baronissi, SA, Italy

关键词: Functional bowel disorder severity index (FBDSI);    Fibromyalgia;    Severity of illness index;    Questionnaires;    Male;    Irritable bowel syndrome/physiopathology;    Irritable bowel syndrome/complications;    Female;    Adult;   

Others  :  1121780
DOI  :  10.1186/1471-230X-14-182

 received in 2013-06-15, accepted in 2014-10-09,  发布年份 2014

【 摘 要 】

Background

Fibromyalgia Syndrome (FMS) is a frequent comorbidity in Irritable Bowel Syndrome (IBS) patients with a higher functional bowel disorder severity index (FBDSI). We tested the possibility that mild to severe IBS patients without FMS would have a graduated visceral and somatic perception, and the presence of FMS would further enhance somatic, but conversely attenuate visceral perception.

Our aim was to study visceral and somatic sensitivity in mild IBS patients and in severe IBS patients with or without FMS.

Methods

Eleven mild IBS and 19 severe IBS with and without FMS patients were studied. Somatic and visceral stimuli were applied in each patient by means of electrical stimulations at active and control sites and by means of an electronic barostat in the rectum. Thresholds for discomfort and perception cumulative scores were measured.

Results

Mild and severe IBS patients without FMS demonstrated a significantly lower somatic perception cumulative score than severe IBS patients with FMS at active site. Conversely only severe IBS patients without FMS had significantly lower visceral thresholds for discomfort than mild IBS patients and severe IBS patients with FMS.

Conclusions

The presence of co-existing FMS or greater FBDSI affects somatic and visceral perception in a graded fashion across IBS patients.

【 授权许可】

   
2014 Tremolaterra et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

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