A multi-centre, non-inferiority, randomised controlled trial to compare a cervical pessary with a cervical cerclage in the prevention of preterm delivery in women with short cervical length and a history of preterm birth – PC study

BMC Pregnancy and Childbirth

Study Protocol

Maud D. van Zijl¹  Liselotte E.M. van Kempen¹  Eva Pajkrt¹  Bouchra Koullali¹  Martijn A. Oudijk¹  Toon A.A.M. Toolenaar²  Dimitri N.M. Papatsonis³  Tom H.M. Hasaart⁴  Joost J. Zwart⁵  Nico W.E. Schuitemaker⁶  Nicole Y.C. Steemers⁷  Marchien van Baal⁸  Anjoke J.M. Huisjes⁹  Marion E. van Hoorn^1,10  Sebastiaan W.A. Nij Bijvank^1,11  Marieke Sueters^1,12  Liesbeth H.C.J. Scheepers^1,13  David P. van der Ham^1,14  Inge M. Evers^1,15  Marinka S. Post^1,16  Dick J. Bekedam^1,17  Brenda B.J. Hermsen^1,18  Karin de Boer^1,19  Flip W. van der Made^2,20  Karlijn C. Vollebregt^2,21  Moira A. Müller^2,22  Federico Prefumo^2,23  Henricus Visser^2,24  Begoña Martinez de Tejada^2,25  Maureen T.M. Franssen^2,26  Marjon A. de Boer^2,27  Nico A. Mensing van Charante^2,28  Angelo B. Hooker^2,29  Josje Langenveld^3,30  Ewoud Schuit^3,31  Christiana A. Naaktgeboren^3,31  Ben W.J. Mol^3,32 

[1] Department of Obstetrics and Gynaecology, Academic Medical Center (AMC), Amsterdam, The Netherlands;Department of Obstetrics and Gynaecology, Albert Schweitzer Hospital, Dordrecht, The Netherlands;Department of Obstetrics and Gynaecology, Amphia Hospital, Breda, The Netherlands;Department of Obstetrics and Gynaecology, Catharina Hospital, Eindhoven, The Netherlands;Department of Obstetrics and Gynaecology, Deventer Hospital, Deventer, The Netherlands;Department of Obstetrics and Gynaecology, Diakonessenhuis, Utrecht, The Netherlands;Department of Obstetrics and Gynaecology, Elizabeth TweeSteden Hospital, Tilburg, The Netherlands;Department of Obstetrics and Gynaecology, Flevoziekenhuis, Almere, The Netherlands;Department of Obstetrics and Gynaecology, Gelre Hospital, Apeldoorn, The Netherlands;Department of Obstetrics and Gynaecology, HagaZiekenhuis, Den Haag, The Netherlands;Department of Obstetrics and Gynaecology, Isala Hospital, Zwolle, The Netherlands;Department of Obstetrics and Gynaecology, Leiden University Medical Center (LUMC), Leiden, The Netherlands;Department of Obstetrics and Gynaecology, Maastricht University Medical Centre (MUMC), Maastricht, The Netherlands;Department of Obstetrics and Gynaecology, Martini Hospital, Groningen, The Netherlands;Department of Obstetrics and Gynaecology, Meander Medical Center, Amersfoort, The Netherlands;Department of Obstetrics and Gynaecology, Medical Center Leeuwarden, Leeuwarden, The Netherlands;Department of Obstetrics and Gynaecology, Onze Lieve Vrouwe Gasthuis (OLVG) Oost, Amsterdam, The Netherlands;Department of Obstetrics and Gynaecology, Onze Lieve Vrouwe Gasthuis (OLVG) West, Amsterdam, The Netherlands;Department of Obstetrics and Gynaecology, Rijnstate Hospital, Arnhem, The Netherlands;Department of Obstetrics and Gynaecology, Sint Franciscus Gasthuis, Rotterdam, The Netherlands;Department of Obstetrics and Gynaecology, Spaarne Gasthuis, Haarlem, The Netherlands;Department of Obstetrics and Gynaecology, Spaarne Gasthuis, Hoofddorp, The Netherlands;Department of Obstetrics and Gynaecology, Spedali Civili di Brescia and University of Brescia, Brescia, Italy;Department of Obstetrics and Gynaecology, Tergooi Hospital, Hilversum, The Netherlands;Department of Obstetrics and Gynaecology, University Hospitals of Geneva and Faculty of Medicine, Geneva, Switzerland;Department of Obstetrics and Gynaecology, University Medical Center Groningen (UMCG), Groningen, The Netherlands;Department of Obstetrics and Gynaecology, VU Medical Center (VUmc), Amsterdam, The Netherlands;Department of Obstetrics and Gynaecology, Westfries Gasthuis, Hoorn, The Netherlands;Department of Obstetrics and Gynaecology, Zaans Medical Center (ZMC), Zaandam, The Netherlands;Department of Obstetrics and Gynaecology, Zuyderland Hospital, Heerlen, The Netherlands;Julius Center for General Practice and Health Sciences, University Medical Center Utrecht (UMCU), Utrecht, The Netherlands;Robinson Research Institute, School of Paediatrics and Reproductive Health, University of Adelaide, Adelaide, Australia;

关键词: Preterm birth;    Prevention;    Cerclage;    Pessary;    Morbidity;   

DOI  :  10.1186/s12884-017-1393-6

 received in 2017-04-14, accepted in 2017-06-22,  发布年份 2017

来源: Springer

【 授权许可】

CC BY   
© The Author(s). 2017