Epidemiology of acute respiratory infections in children - preliminary results of a cohort in a rural north Indian community

BMC Infectious Diseases

Research Article

Siddhartha Saha¹  Marc-Alain Widdowson¹  Renu Lal¹  Kathryn E. Lafond¹  Fatimah Dawood¹  Puneet Misra²  Anand Krishnan²  Sanjay Rai²  Chandrakant S. Pandav²  Abhishek Wahi²  Debjani Ram Purakayastha²  Vishnubhatla Sreenivas³  Rizwan Abdulkader Suliankatchi⁴  Arti Kapil⁵  Ritvik Amarchand⁶  Shobha Broor⁶  Suresh K. Kapoor⁶  Vivek Gupta⁶ 

[1] Centers for Disease Control and Prevention, 30333, Atlanta, GA, USA;Centre for Community Medicine, All India Institute of Medical Sciences, 110029, New Delhi, India;Department of Biostatistics, All India Institute of Medical Sciences, 110029, New Delhi, India;Department of Community Medicine, Velammal Medical College Hospital and Research Institute, 625009, Madurai, India;Department of Microbiology, All India Institute of Medical Sciences, 110029, New Delhi, India;The INCLEN Trust International, 110020, New Delhi, India;

关键词: Acute respiratory infections;    Burden;    Children;    Cohort;    Developing countries;    Epidemiology;    Pneumonia;   

DOI  :  10.1186/s12879-015-1188-1

 received in 2015-03-04, accepted in 2015-10-07,  发布年份 2015

来源: Springer

【 摘 要 】

BackgroundDespite acute respiratory infections being a major cause of death among children in developing countries including India, there is a lack of community-based studies that document its burden and aetiology.MethodsA dynamic cohort of children aged 0–10 years was established in four villages in a north Indian state of Haryana from August 2012 onwards. Trained health workers conducted weekly home visits to screen children for acute respiratory infection (ARI) defined as one of the following: cough, sore throat, nasal congestion, earache/discharge, or breathing difficulty. Nurses clinically assessed these children to grade disease severity based on standard age-specific guidelines into acute upper or lower respiratory infection (AURI or ALRI) and collected nasal/throat swabs for pathogen testing.ResultsOur first year results show that ARI incidence in 0–10 years of age was 5.9 (5.8–6.0) per child-year with minimal gender difference, the ALRI incidence in the under-five age group was higher among boys (0.43; 0.39–0.49) as compared to girls (0.31; 0.26–0.35) per child year. Boys had 2.4 times higher ARI-related hospitalization rate as compared to girls.ConclusionARI impose a significant burden on the children of this cohort. This study platform aims to provide better evidence for prevention and control of pneumonia in developing countries.

【 授权许可】

CC BY   
© Krishnan et al. 2015