Epidemiology of acute respiratory infections in children - preliminary results of a cohort in a rural north Indian community

BMC Infectious Diseases

Marc-Alain Widdowson¹  Renu Lal¹  Suresh K. Kapoor⁶  Shobha Broor⁶  Chandrakant S. Pandav⁵  Fatimah Dawood¹  Arti Kapil⁴  Vishnubhatla Sreenivas³  Abhishek Wahi⁵  Debjani Ram Purakayastha⁵  Puneet Misra⁵  Sanjay Rai⁵  Siddhartha Saha¹  Rizwan Abdulkader Suliankatchi²  Kathryn E. Lafond¹  Vivek Gupta⁶  Ritvik Amarchand⁶  Anand Krishnan⁵ 

[1] Centers for Disease Control and Prevention, Atlanta 30333, GA, USA;Department of Community Medicine, Velammal Medical College Hospital and Research Institute, Madurai 625009, India;Department of Biostatistics, All India Institute of Medical Sciences, New Delhi 110029, India;Department of Microbiology, All India Institute of Medical Sciences, New Delhi 110029, India;Centre for Community Medicine, All India Institute of Medical Sciences, New Delhi 110029, India;The INCLEN Trust International, New Delhi 110020, India

关键词: Pneumonia;    Epidemiology;    Developing countries;    Cohort;    Children;    Burden;    Acute respiratory infections;   

Others  :  1232807
DOI  :  10.1186/s12879-015-1188-1

 received in 2015-03-04, accepted in 2015-10-07,  发布年份 2015

【 摘 要 】

Background

Despite acute respiratory infections being a major cause of death among children in developing countries including India, there is a lack of community-based studies that document its burden and aetiology.

Methods

A dynamic cohort of children aged 0–10 years was established in four villages in a north Indian state of Haryana from August 2012 onwards. Trained health workers conducted weekly home visits to screen children for acute respiratory infection (ARI) defined as one of the following: cough, sore throat, nasal congestion, earache/discharge, or breathing difficulty. Nurses clinically assessed these children to grade disease severity based on standard age-specific guidelines into acute upper or lower respiratory infection (AURI or ALRI) and collected nasal/throat swabs for pathogen testing.

Results

Our first year results show that ARI incidence in 0–10 years of age was 5.9 (5.8–6.0) per child-year with minimal gender difference, the ALRI incidence in the under-five age group was higher among boys (0.43; 0.39–0.49) as compared to girls (0.31; 0.26–0.35) per child year. Boys had 2.4 times higher ARI-related hospitalization rate as compared to girls.

Conclusion

ARI impose a significant burden on the children of this cohort. This study platform aims to provide better evidence for prevention and control of pneumonia in developing countries.

【 授权许可】

   
2015 Krishnan et al.

【 图 表 】

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